It is hard to describe how fun it was to yell at people about the immune system at this shindig.

#PublicationFriday📚 In this recent paper, #SCGE PIs ErikSontheimerLab and Wen Xue use multiomics to identify elements of hepatoblastoma, a rare tumor of the liver pubmed.ncbi.nlm.nih.gov/35932276/

Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing go.nature.com/3KlMaFA

#SCGE PIs Daniel Anderson of Massachusetts Institute of Technology (MIT) and Guangping Gao and Wen Xue of UMass Chan Medical School designed a new nanoparticle for highly efficient RNA delivery to the lungs. Read more ⬇️ #nanoparticles #RNAdelivery #geneediting #therapeutics

Koch Institute at MIT MIT ChemE Dept Leslie Dan Faculty of Pharmacy RNA Therapeutics Institute UMass Chan Medical School Boston Children's MIT IMES Li Weibo Institute for Rare Diseases Research Wen Xue Bowen LI New nanoparticles can perform gene editing in the lungs #NBTintheNews via Massachusetts Institute of Technology (MIT) news.mit.edu/2023/new-nanop…

PE-Tag developed by Scot Wolfe and team @UMassMedical is an efficient genome-wide approach to map off-target effects of in vitro and in vivo genome editing. nature.com/articles/s4159…

And read the Research Briefing here: nature.com/articles/s4159…

Join #SCGE investigator Shunqing Liang, PhD at #ASGCT23 for a presentation on "Develop combinatorial non-viral and viral CRISPR delivery for lung diseases." 📍: SCGE Scientific Symposium 🗓️: May 19 ⏰: 11:00 AM Symposium agenda: annualmeeting.asgct.org/program/agenda…

Congrats to Wen Xue, PhD, Scot Wolfe, PhD, and Erik Sontheimer, PhD, for receiving a new National Cancer Institute grant to use in vivo prime editing for #precision #cancer models. Wen Xue @ESontheimer_lab Scot Wolfe @UmassChan RNA Therapeutics Institute

T-10 days to the '25 Years of Lowe Lab' Reunion! Looking forward to welcoming back 80+ alumni for two days of science, memories, and catching up. Will continue to highlight lab alums over the coming days. #LoweLab25

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates go.nature.com/48hmu76

Lars was also a great co-mentor to students. He and Wen Xue teamed up on some of the most important papers from the lab. Wen now has his own lab focusing on genome editing UMass Chan Medical School – check it out Wen Xue! -SWL #LoweLab25

Lowe Lab (2005-2015)

I am honored to attend the Lowe lab 25 years reunion. Lots of great memories. Thank you, Scott!

The Wen Xue's paper is the last one standing from UMass, so please help our colleagues continue on to the Elite Eight by voting again; five days left of voting! Click on the link below, sign in, look for UMass Chan icons, and VOTE! statnews.com/feature/stat-m…

The RTI & UMass Chan Medical School Medical School seeks the next generation of scientific leaders! Join our research community as a Maraganore Early Independence Fellow. Get 3-5 years of support. Apply by Dec 1 to join us: academicjobsonline.org/ajo/jobs/28425

The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cells go.nature.com/3X6mOBv

Prime assembly with linear DNA donors enables large genomic insertions biorxiv.org/content/10.110… #biorxiv_biochem