We're Hiring! Assistant Professor of Biochemistry, Biophysics, and Structural Biology in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF04562

bioRxiv: H/ACA snoRNP guides ribosomal RNA subdomain folding in a satellite particle before joining the core 90S pre-ribosome dlvr.it/TCynHY

First structure of a H/ACA snoRNP acting in ribosome synthesis. In a great collaboration with the Hurt lab, we provide a detailed structural and biochemical view of the snR30 snoRNP guiding local 18S rRNA subdomain folding. 👇👇👇

Our results finally explain the essential role of snR30 snoRNA! Check out the details in our preprint to find out more 👉👉👉 biorxiv.org/content/10.110… #ribosome #cryoEM #RNA

Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV | bioRxiv biorxiv.org/content/10.110…

biorxiv.org/content/10.110…

I'm excited to share our latest review on mistranslation of the genetic code. I had a great time working with all the authors. A special shout-out to the talented Dominik B. Schuntermann, whose creativity and determination were instrumental. jbc.org/article/S0021-…

bioRxiv: The RNA helicase HrpA rescues collided ribosomes in E. coli dlvr.it/TD7XvQ

We’ve captured the splitting image of Slh1: our work on an enzyme that splits collided ribosomes in E. coli is out on bioRxiv! Huge thanks to the Beckmann Lab, Burroughs, and Aravind for a great collaboration. biorxiv.org/content/10.110…

🚨 New paper alert! 🚨 We introduce a novel method for accurate, sensitive, and fast tRNA quantification without the biases of traditional RNAseq. academic.oup.com/nar/article/do… Nucleic Acids Res

Check the description of the new SubtiWiki framework by Christoph Elfmann Vincenz Dumann and Tim van den Berg. Enjoy the many new features! Uni Göttingen IMPRS for Genome Science #SubtiWiki biorxiv.org/content/10.110…

The ever amazing Artyom Egorov in our group has made a new visualisation tool for comparative genomics. Makes particularly beautiful images of phages, plasmids, other MGEs or regions of prokaryotic genomes 😍 biorxiv.org/cgi/content/sh…

This is big! Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 Fresh out in The Lancet including age- and geo-resolved data and predictions. thelancet.com/journals/lance…

By 2050, around 2 million people — the majority aged over 70 — could die from drug-resistant infections each year go.nature.com/4e8E9jO

We're excited to announce the publication of our latest study on the identification of a novel tRNA modification, 2-aminovaleramididine (ava2C), and its molecular basis on decoding. Congratulations and thanks to our wonderful collaborators! rdcu.be/dUr0l

We are looking for a highly motivated PhD student to explore molecular mechanisms of protein synthesis using fast kinetics and cryo-EM. Pls share the link or apply! uu.varbi.com/en/what:job/jo…

Apply for the Early Independence Fellows program UMass Chan Medical School and RNA research RNA Therapeutics Institute. Additional info: brnw.ch/21wMIg9

The coming microbial crisis: Our antibiotic bubble is about to burst science.org/doi/10.1126/sc…

How does the human #ribosome machinery select an open reading frame on mRNA for translation? Check out our #cryoEM work NatureStructMolBiol: rdcu.be/dUbMg Thanks to all involved - most of all first author Valentyn Petrychenko and our collaborators from the Rodnina lab MPI for Multidisciplinary Sciences. 1/5

A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome | Research Square researchsquare.com/article/rs-505…