We identified SAMD9 as a common sensor of cytosolic dsDNA and dsRNA molecules and a key host restriction factor of the infection of multiple dsRNA viruses in vitro and in vivo! rdcu.be/eiJHa

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

Congratulations to Mikey Grunst, #PhD! YaleMicroPath Yale School of Medicine medicine.yale.edu/micropath/news… #spikeprotein #microbiology

Congrats to the authors ⁦Yale University⁩ on this exciting and important work! #BrainTCellsRule || The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour | Nature nature.com/articles/s4158…

In a new nature study, Yale Department of Immunobiology and Yale Internal Medicine researchers say newly-discovered #TCells in the #brain carry information from the gut, with implications for conditions like #Parkinsons disease and multiple sclerosis: medicine.yale.edu/news-article/t…

For anyone who has had a federal grant cancelled, consider filling out this congressional survey for the Committee on Science, Space, and Technology (you can be on the record or anonymous) forms.office.com/pages/response…

How to pick the right lab for a postdoc if you want to stay in academia. [based on my experience in the US and partly Europe] 1. Make a list of possible groups in advance. Meet their students & postdocs at conferences. Listen to their feedback. Get opinions from the faculty in

On leadership & support- meet the amazing first responder team (partial) who voluntarily worked during first 12h, in darkness, smoke, and ashes, to save a building's precious frozen biological samples (most saved). No words to describe the courage and dedication of these people.

On Sunday I traveled to the middle of the desert to capture this: The ISS against our sun. What I didn't expect: the sun producing a magnificent flare at the same time A once-in-a-lifetime shot I'm thrilled to share with you. See the uncropped shot or get the print in the reply

news.yale.edu/2025/06/23/scr… Yale Lab Medicine Yale School of Medicine Yale Medicine

A new paper discussing the importance of federal, institutional, and programmatic support for physician scientist trainees. The same can easily apply to biomedical trainees. We as a nation need to support the next generation of doctors and researchers! rdcu.be/etaiE

Memory T cell formation and phenotype varies across intestinal compartments: mucosalimmunology.org/article/S1933-…

The July issue of Science #Immunology is out! This month's cover features a study that demonstrates how the transcription factor #SpiB regulates #TuftCell activation within the gut by inhibiting c-Kit and TSLP signaling. Read this research and more: scim.ag/3TiI6tB

By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers in Science have enabled ear tissue regeneration in mice. Learn more: scim.ag/44muTVr

Check out our paper Madison (Maddi) Strine, PhD Kerri St. Denis Yale Pediatrics Yale Department of Immunobiology

New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats Aman Kumar Robyn Tamblyn and the rest of the team. nature.com/articles/s4158…

Writing = Thinking Don't outsource it to AI

#WeekendRead! #EveryCellIsAnImmuneCell! Kaelberer Bohorquez &co show nature that via #TLR5 flagellin drives neuropeptide PYY release by gut colonic neuropod cells, activating vagal neurons that signal to #brain, reducing feeding via a “neurobiotic sense”! nature.com/articles/s4158…