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Sam Rodriques Jake P. Taylor-King Actually as Jake points out this was obvious idea and a quick search of the literature and basic understanding of ECM, vascular reg and AMD would lead you to Rho/RACK Plus this 2022 article directly tests targeting Rho system re dry AMD …thsocjournals.onlinelibrary.wiley.com/doi/10.1002/pa…

Sam Rodriques Jake P. Taylor-King Elicit is really good at seeing if things like this are novel. ROCK inhibitors have been looked at for dry AMD : elicit.com/review/154212b… And using them to increase phagocytosis for dry AMD is also in the literature: elicit.com/review/2afe437…

God damn it Sam Bowman --- you've YIMBY-pilled me. Bloomsbury Resident's Action Group opposing LifeArc lab build... they're really trying every angle to stop it.

Jake P. Taylor-King LifeArc Obscene – lying to block a medical research lab really is the lowest of the low.

I'm skeptical. owl (in SF june 16th-27th) covered this really well. owlposting.com/p/what-happene…

How is this different to the one you published 6 months a go? cell.com/cell/fulltext/… Man, so many "perspective" pieces out, can't we give it a rest already? I admit, I'm as bad the rest of you but we at least had some maths: arxiv.org/abs/2501.19178

New post: How not to evaluate an AI scientist wildtypehuman.substack.com/p/how-not-to-e…

Now this I like.. perfect timing with new blog post: How not to evaluate an AI scientist. wildtypehuman.substack.com/p/how-not-to-e…

A different analysis: runaway complexity… we need to move towards radical simplification open.substack.com/pub/wildtypehu…

Did a brief interview with Front Line Genomics on sctrends.org and our views on what works in single-cell/spatial 'omics! Write up here: hubs.la/Q03qCBPQ0

From our CEO at Relation: ft.com/content/6e5754…

Waiting for your comment Jamie Timmons ;)

Jake P. Taylor-King 😂 Steve blocked me replying ever since I showed the 2016 email where he lied about having a muscle clock (he didn't have one; it came 7yr later and that one doesn't work). It's remarkably difficult to get across how silly this work is. A set of unusable (little meaningful

All convos I've had go something like... Q: What is epigenetic clock? A: Well, we built a predictor of age using epigenetics Q: Isn't it just picking up disease signatures that correlate to aging? A: Oh certainly not, this is a *separate* biological process. Q: So if I improve

“City advisers say London’s IPO hopes for 2025 now rest largely on a tinned tuna business.” on.ft.com/43HxwSU