New Research: Small extracellular vesicles derived from four dimensional-culture of mesenchymal stem cells induce alternatively activated macrophages by upregulating IGFBP2/EGFR to attenuate inflammation in the spinal cord injury… frontiersin.org/articles/10.33… #bioengineering #biotech

Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall biorxiv.org/cgi/content/sh… #bioRxiv

Similar but distinct: the impact of biomechanical forces and culture age on the production, cargo loading, and biological efficacy of human megakaryocytic extracellular vesicles for applications in cell and gene therapies biorxiv.org/cgi/content/sh… #bioRxiv

New Research: Bacterial extracellular vesicles and associated functional proteins in fermented dairy products with… #microbiology frontiersin.org/articles/10.33…

Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma? | Bruno Sarmento i3S-Instituto de Investigação e Inovação em Saúde | Bruno Sarmento CRS Spanish Portuguese Local Chapter #cancervaccine #genetherapy #exosome #tumormicroenvironment doi.org/10.1016/j.jcon…

Exosomal microRNA signature from plasma-derived extracellular vesicles in gastric cancer biorxiv.org/cgi/content/sh… #bioRxiv

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles biorxiv.org/cgi/content/sh… #bioRxiv

Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery biorxiv.org/cgi/content/sh… #bioRxiv

Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma? | Bruno Sarmento i3S-Instituto de Investigação e Inovação em Saúde | Bruno Sarmento CRS Spanish Portuguese Local Chapter [50 days' free access] #exosome #glioblastoma authors.elsevier.com/sd/article/S01…

Differentiation of Large Extracellular Vesicles in Oral Fluid: Combined Protocol of Small Force Centrifugation and Pattern Analysis biorxiv.org/content/10.110…

High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy biorxiv.org/cgi/content/sh… #bioRxiv

Happy to share our finding of #tau filaments within brain extracellular vesicles in #Alzheimers disease using #cryoET, #cryoEM and #mass_spec. Great work by co-first authors Dr. Steph Fowler and Tiana Sophia Behr, and with Duff Lab. Preprint➡️ biorxiv.org/content/10.110… Thread⬇️

#ERCC19 Julie Saugstad OHSU News Differential effects of ApoE genotype on microRNA cargo of cerebrospinal fluid extracellular vesicles in females with Alzheimer’s disease compared to males pubmed.ncbi.nlm.nih.gov/35573689

Solid tumor EV cluster bombs inhibit CAR T cells - small extracellular vesicles carry tumor antigens & immune checkpoint PD-L1, preferentially interact w cognate CAR T cells inhibiting proliferation, migration, & function aacrjournals.org/cancerres/arti…

Diet, commensal microbiota-derived extracellular vesicles, and host immunity. - Taitz JJ et al. - dx.doi.org/10.1002/eji.20… #microbiome

Sox9 Regulates Extracellular Matrix Stiffness during Vascular Smooth Muscle Cell ageing by increased secretion of LH3 via extracellular vesicles. biorxiv.org/cgi/content/sh… #bioRxiv

New Research: Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability: Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers… #immunology frontiersin.org/articles/10.33…

#PeerReview from eLife - the journal of 👉🏿 Improved Isolation of Extracellular Vesicles by Removal of Both Free Proteins and Lipoproteins biorxiv.org/content/10.110… #bioRxiv #reviewedpreprint

Extracellular vesicles of Pseudomonas aeruginosa downregulate pyruvate fermentation enzymes and inhibit the initial growth of Staphylococcus aureus pubmed.ncbi.nlm.nih.gov/37131486/

We are happy to share with all EVs aficionados our secrete recipes to get the best TEM pictures of extracellular vesicles. FrenchSocEVs ISEV researchgate.net/publication/37…