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Peripheral Beta-Blockade Differentially Enhances Cardiac and Respiratory Interoception biorxiv.org/content/10.110… #biorxiv_neursci

1/ We can measure interoception in many aspects, but can we actually manipulate it? I’m excited to share our new study, which shows that blockade of peripheral beta-adrenergic pathways improves cardiac and respiratory interoception in unique ways! 🧵👇biorxiv.org/content/10.110…

Beyond happy to share this study with you - Ashley and the team have really exceeded all expectations. Computational modelling of drug effects on multi-domain interoception!

Can we enhance interoception by controlling the heart? Thrilled to share our new study, led by Ashley Tyrer, where we use computational modeling to show that blockading peripheral noradrenaline uniquely alters awareness of heart rate & breathing! biorxiv.org/content/10.110… 🧵👇 pic.x.com/uMz9rXYglH

I don't get on X much any more, but it was worth doing it to come across this really interesting study. Well worth a read...

Excited to share our latest publication, out now in Science Advances: “Thermosensory predictive coding underpins an illusion of pain.” science.org/doi/10.1126/sc…. Read the full thread below for details!

We compared multiple computational models and found a two-level Hierarchical Gaussian Filter best explained our data. First-level uncertainty shaped temperature sensations: stronger expectations of cold amplified cold feelings, while stronger warm predictions enhanced warmth.

In contrast, second-order uncertainty, reflecting how unsure you are about the precision of your own predictions, actually intensified the illusion of pain. This means that when thermal expectations are uncertain, the brain interprets these ambiguous stimuli as more painful!

Using quantitative MRI, we linked thermal learning parameters to brain microstructure. Notably, decision temperature correlated with iron content in the Subnucleus Reticularis Dorsalis (SRD), a key structure in descending pain modulation.

Pleased to share our latest collaborative publication, "Thermosensory predictive coding underpins an illusion of pain", out now in Science Advances! The first major output of our Visceral Mind Project, lead by the amazing Francesca Fardo and her team! science.org/doi/full/10.11…

I had the pleasure of chatting with the brilliantly insightful Sarah Crespi on the Science Magazine podcast about what it means to experience an illusion of pain based on science.org/doi/10.1126/sc…! Catch the full interview starting at 26:44. science.org/content/podcas…

Dive deep into neuroscience in the NAD PhD programme 🧠 Meet Neuroscience Academy Denmark fellow Kelly Hoogervorst, PhD student at CFIN 🧠, and learn why you should apply for a fully funded NAD PhD fellowship. Applications open May 1 - read more 👉 neuroscienceacademydenmark.dk/phd-programme/

I can't actually believe this but I got a Lundbeck Postdoctoral Fellowship! 🤯 I'm so excited to work on multi-organ brain-body interaction models with Micah G. Allen , Anke Karabanov , Dani S. Bassett, & Diego Vidaurre! I'm honestly in shock and can't wait! 🎉

Congratulations Leah - truly a well earned Fellowship!

Check out this video showcasing Kelly's PhD on metacognition in our lab! Well done!

Our students are running a short survey on interoception, ADHD, and autism. They’d be super grateful if you could take it & share! 👉 docs.google.com/forms/d/e/1FAI… #ADHD #Autism #interoception #psychscience

Do you have #ADHD or #autism? We're running a short, anonymous survey on interoception. It takes just 15–20 minutes, and your input would mean a lot. 👉 docs.google.com/forms/d/e/1FAI…

How much you ‘body-wander’ could affect your mental health psyche.co/ideas/how-much… Fascinating Psyche magazine Idea by Leah Banellis The ECG CFIN 🧠 Some people tune into bodily sensations while daydreaming, others don’t – with implications for anxiety, depression & ADHD

I'm so grateful to write my first magazine article with Psyche Magazine! It was a real pleasure to work with Christian Jarrett 🇺🇦 on this piece. It highlights our preprint on 'Body-Wandering' with invaluable guidance from Micah G. Allen and Jonny Smallwood: biorxiv.org/content/10.110…