Serum pTau-181 and nFL best predicted worsening cognition in those w subjective cognitive complaints or MCI, with serum amyloid having modest predictive value

Associations Between Blood-Based Biomarkers and Cognitive and Functional Trajectories Among Participants of the MEMENTO Cohort | Neurology neurology.org/doi/10.1212/WN…

Planche et al. combined multiple MRI datasets to extrapolate lifetime volumetric models for brain structures in healthy aging and #progressivesupranuclearpalsy-Richardson syndrome. Vincent Planche shorturl.at/FzVMt

I’m happy to share our latest work on the spatiotemporal evolution of infarct volumes in ischemic stroke due to large vessel occlusion !! Three groups (fast, intermediate and slow progressors) with different clinical and radiological characteristics were identified. Neurology Journal

🗓️Today was the first edition of the Neurodegenerative Disease Day symposium in the Centre Broca🙌 Sara Carracedo, Erwan Bezard, Léa Bonamy and Vincent Planche were among the speakers 🎙️ Bordeaux Neurocampus | #brain #neurodegenerative

This study unveiled infarct growth charts for #stroke progression that offer a novel and practical approach for phenotype identification in stroke patients and outcome estimation, all without relying on advanced postprocessing techniques: bit.ly/4e4LKQO Fanny Munsch

Last year, in JAMA Neurology we discussed with Vincent Planche the uncertainty of whether there was an actual disease-modifying mechanism of lecanemab to explain efficacy and predict long-term increasing effects. Preliminary OLE data from Eisai Global appears to confirm our concerns..

Centre de Neurologie Cognitive JAMA Neurology Vincent Planche Eisai Global Interestingly both Dennis Selkoe and John Hardy supported our symptomatic effect hypothesis when justifying the Rx should not be discontinued sciencemediacentre.org/expert-reactio…

Very proud to see our new publication with Vincent Planche in Nat Rev Neurol! We are challenging biological definitions of neurodegenerative diseases. Big thanks to #BernardHanseeuw! Stay tuned for a thread! OA: rdcu.be/dQmvo

🚨Paper Alert🚨 New piece with Vincent Planche! We discuss the risks of #Alzheimer #Parkinson biological definitions, emphasize linking disease definitions w/ clinical outcomes, and clinicobiological frameworks to disentangle multiple diseases Thread👇🏻 1/ rdcu.be/dQmvo

Our point of view in one slide (also with the idea of extending the concept beyond AD):

Our point of view in one slide (also with the idea of extending the concept beyond AD):

🚨The Great Debate in Diagnosing Alzheimer Disease: More Than Just a β Test🚨in my accompanying Editorial Neurology Journal as supported by the excellent & necessary collaborative study led by Eduardo Zimmer Zimmer Lab et al! Special thx to Melissa Paretsky! dx.doi.org/10.1212/WNL.00…

#SaveTheDate| Participez à la 7ème édition des Entretiens Alzheimer à #Bordeaux ! 🗓️ 7/10/2024, 14h-17h30 📍 Palais de la Bourse Programme : actualité de la recherche, diagnostic précoce, burn-out des aidant et traitements 🎟️ Gratuit ! Inscrivez-vous ici: entretiensalzheimer.org/index.php/bord…

Venez nombreux! CHU de Bordeaux Bordeaux Neurocampus

♥️IWG♥️ jamanetwork.com/journals/jaman…