“give yourself a lot of shots to get lucky” is even better advice than it appears on the surface. luck isn’t an independent variable but increases super-linearly with more surface area—you meet more people, make more connections between new ideas, learn patterns, etc.

We have an amazing speaker lineup for the upcoming 8th Annual Mutational Scanning Symposium! "Mapping and Modelling Variant Effects at Scale" #VariantEffect25📍Barcelona 🗓️ May 21-23, 2025 varianteffect.org/mss2025🧵1/3

Last day to submit abstracts for mSBW2025! We have a great lineup of speakers with exciting talks about synthetic biology and mammalian cell engineering. Come join us! #synbio

Never could I have imagined that ABE would someday enable such a transformative outcome for a child. Thank you Kiran Musunuru, Rebecca Ahrens-Nicklas, and KJ’s family for having the courage to demonstrate to the world what is possible. Incredible. 💕 nytimes.com/2025/05/15/hea… via

Tesla Being born with no hands, FSD is a life changer, thank you! #tesla #TSLA #Cybertruck

On this #DIPG Awareness Day, I am thinking about all the children, adolescents and adults struck by this terrible brain cancer, and the urgent need to honor them by supporting scientific research towards a cure. #DIPGAwareness #ScienceMatters

The Angel of Grief #DIPGAwareness

Another medical milestone! The first patient treated with a prime edited therapeutic shows positive clinical outcomes consistent with effective rescue of his chronic granulomatous disease (CGD), a debilitating and life-shortening primary immunodeficiency. At least 19 base editing

CRISPR-BEasy, our web tool for designing tiling libraries for base editing screens, was published last Friday in NAR (sorry, I am late). Goal: To make base editing screens accesible to all! Quick thread below with key features crispr-beasy.cerc-genomic-medicine.ca/# academic.oup.com/nar/advance-ar…

On the days I feel lost, I return to this, and it always reignites me.

does anyone use outlook on your browser? do you want support for an agent to go read and send emails and schedule stuff for you?

Graduating from cute to cuter, thanks to #GeneTherapy 🧪

🚨 New Preprint 🚨 A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype How can we tune JAK/STAT signaling to create better immune cell therapies? doi.org/10.1101/2025.0…

It’s hard to believe it’s been 20 years since Steve told Stanford graduates to stay hungry and stay foolish. His powerful advice still rings true, and I hope it helps guide this year’s new grads as they begin their journey to become tomorrow’s leaders. stevejobsarchive.com/exhibits/stay-…

If we settle for anything less with AI, we’ll be failing to act on what’s possible. For new graduates, this is not just a time to survive disruption but one to shape what comes next. You can read my full thoughts in today's The San Francisco Standard : sfstandard.com/opinion/2025/0…

When we came to see our destroyed labs hit by an Iranian missile, we found that a piano had survived Weizmann Institute

Two collaborative papers with Karl Deisseroth, 21 years apart, (with daily collaboration in life during the intervening period.) I will provide a full explainer thread on this study shortly, but have to first say how fun it is to do science with this brilliant guy☺️

🚨NEW - In vivo CAR T cell generation to treat cancer and autoimmune disease Capstan Therapeutics direct delivery of mRNA-encoded CARs to CD8+ T cells in mouse & NHP models shows tumor control not only in blood, but also tissue. Immune reset seen at B cell recovery science.org/doi/10.1126/sc…

Many have asked what is our secret recipe for recovery. In reality there is only one way- you start as fast as you can and slowly accelerate

We mourn the loss of our beloved department member, Prof. Zelig Eshhar — a visionary immunologist and pioneer of CAR-T cell therapy. His groundbreaking work revolutionized cancer treatment and gave hope to countless patients.