Epigenome editing is transforming biological sciences and medicine. We're grateful for the opportunity to publish this review of the field in Nature Biotechnology. Check it out here: rdcu.be/dPjsJ

Interested in using stem cells to create more mature human cortical neurons for studying intact living brain circuits? Excited to share our Nature Protocols Omer Revah, Felicity Gore, Konstantin Kaganovsky, Xiaoyu Chen, Karl Deisseroth, Sergiu P. Pasca nature.com/articles/s4159…

Please hold the date for the next CORTICAL DEVELOPMENT MEETING in Giardini Naxos, Sicily, Italy - May 25-28, 2025 @corticaldev2022 Arnold Kriegstein Gord Fishell Flora Vaccarino

The next installment of the ‘Mediterranean’ Cortical Development meeting will take place in Sicily next year! Hoping to see you all there.

We are delighted to be a part of several exciting collaborative projects and are looking for a senior scientist to lead organoid generation and analysis for these projects, with room to develop independent projects as well. Please apply or share! recruit.apo.ucla.edu/JPF09796

Debra Silver, PhD, has been honored with the 2024 Javits Award from NIH for her groundbreaking work on intellectual disability and autism. Her research on radial glia cells continues to illuminate the complexities of neurological disorders. Debby Silver medschool.duke.edu/news/debra-sil…

Please RT: We are hiring! Apply to join the exciting research going on Duke Department of Cell Biology! jobs.sciencecareers.org/job/662805/fac…

Come see us at #SfN2024 in Chicago! The Duke Neurobiology Graduate Training Program booth will be open from 📅Saturday to Tuesday, ⏰12-2 PM. Meet with students, faculty, and learn about joining our world-class research community Duke Neurobiology!

Are you attending #SfN24 and interested in brain development? Please join us for the cortical development nano symposium on October 8 at 8:00 AM!

I am very proud to present Dr. Beika Zhu's work: biorxiv.org/cgi/content/sh…

I am delighted to inform everyone that the next tri-annual Cortical Development meeting to be held in Sicily is now online and available for registration: corticaldevelopment.wordpress.com Looking forward to hearing from and seeing everyone in this beautiful and historic site!

🧬 A Quantum leap in single cell analysis! Read our blog introducing Quantum Barcoding: - 2M cells in just 1.5 days - 75% less hands-on time - Costs as low as $0.01/cell - Up to 9,216 samples per run Learn more ⬇️ hubs.la/Q02Y_Kws0

Congratulations Li, another impressive achievement with interesting implications and a resource for our field. Well done!

1/ I am beyond thrilled to share our new paper in Cell! We explored the regulatory principles underlying pleiotropy in psychiatric disorders. cell.com/cell/abstract/…

Despite the trying times, thrilled to share our Nature Protocols piece on massively parallel in vivo Perturb-seq: nature.com/articles/s4159…

In Cell Reports, Arantxa Cebrian-Silla, Arturo Alvarez-Buylla, PhD, and their colleagues show that B2 cells are an important population of secondary neural stem cells that sustain neurogenesis in adult mice: doi.org/10.1016/j.celr… UCSF Broad Stem Cell

My lab is hiring 2 postdocs on a NIH-funded grant characterizing molecular & cellular changes in the human brain across menopausal transition. Other neuroepigenomics projects are also available. We plan to hire a wet lab scientist & a bioinformatician. Please RT! More info 👇

I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with Walter Isaacson & Christiane Amanpour on Amanpour and Company, airing on PBS tonight at 11 pm ET, and on CNN International earlier today. Pls share! youtube.com/watch?v=8YhJM6…

In Nature Genetics we report that base editing of trinucleotide repeats (TNRs) reduces somatic repeat expansions in Huntington’s disease (HD) and Friedreich’s ataxia (FRDA)—in patient-derived cells and in vivo—a collaboration with the Mouro Pinto lab. drive.google.com/file/d/1on7kdy… 1/14

Our paper on cell type-specific changes in dup15q syndrome during development and in the adult human brain is out in NatureComms: nature.com/articles/s4146…. Thanks to the co-first author Yonatan Perez, Arnold Kriegstein and all authors. Special thanks to donors and Autism BrainNet!