Great work by Matteo Trovato and the team. Go check it out!

“Epigenetic context has a strong effect on [transcription factor] affinities, whereas motif sequence does not account for most variation” -Highlight by Michael Fletcher nature.com/articles/s4158…

simultaneous #single_cell #HiC and #RNA_seq shows that widespread chromatin rewiring occurs before transcription activation during lineage specification ⁦Science Magazine⁩ science.org/doi/10.1126/sc…

We are looking for a #PhD candidate! Are you interested in #chromatin and want to combine high-throughput methods & molecular biology to understand how histone #PTMs regulate chromatin functions using #yeast? 👩‍🔬🧑‍🔬🧫🧬 Contact us 👇Please spread the word!

Interested to do scATAC-seq for your projects? Consider joining the course we are organizing with the Zaugg group at EMBL! Both practical and computational hands-on work and lectures about sample prep, the newest methods, and cool applications! 🧬 🧫 🥼 ✨

Happy to see our new preprint out 🥳🥳. In this project we have analyzed how developmental genes can contribute to strengthen the insulation of their own regulatory domains. We hope you enjoy the reading! Alvaro Rada-Iglesias Gene Regulation Thais Ealo

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease biorxiv.org/cgi/content/sh… #bioRxiv

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage ... biorxiv.org/cgi/content/sh… #biorxiv_genomic

Happy to see the SUM-seq preprint out - our approach for scalable droplet-based single-cell ATAC+RNA (up to 1M cells, hundreds of samples)! 🧬 biorxiv.org/content/10.110…

Seeking a cost-effective, scalable single-cell multiomic sequencing method? 🔍🧬 Meet SUM-seq: ATAC + RNA in single nuclei! Check the latest preprint from Noh and Judith Zaugg groups EMBL! Huge congrats to Sara Lobato, Umut Yildiz, Annique Claringbould, Mikael Marttinen, and all authors! 🎉

Berlin Stem Cell Club is on 11 Jan at 16:15 - please join on-site or via Zoom the excellent talks by Kyung-Min Noh EMBL and Daria Bunina Max Delbrück Center. Info here bit.ly/GSCNBSCC. #stemcells #stammzellen #chromatin #research TU Berlin MDC-BIMSB MPI of Immunobiology & Epigenetics Berlin Institute of Health

WARNING Sequence alignment based methods miss most evolutionary conserved enhancers! A fantastic effort led by @mphan232 describes a new strategy and finds 1000s of #conserved #enhancers in distantly related genomes capitalizing on #IPP by Tobias Zehnder 👇 biorxiv.org/cgi/content/sh…

CRISPR has the potential to cure many genetic diseases, but it’s notoriously hard to use in neurons. In this work we tackled 2 of the main hurdles: Cas9 delivery and DNA repair. And we discovered… The rules of genome editing are different in neurons👇🏾 biorxiv.org/content/10.110…

On this day, 50 years ago, EMBL was established! Today, we celebrate five decades of EMBL, fuelled by infinite curiosity. EMBL turns 50, and we’d like to extend a huge thank you to everyone who contributed to reaching this milestone! #EMBL50

Kyung Min Noh, an EMBL Group Leader from South Korea, has been awarded a DKK 20 million grant by the Novo Nordisk Foundation. Over the next seven years, Professor Noh will lead groundbreaking research at Aarhus University's Department of Biomedicine, focusing on chromatin

And that's a wrap! The Transcription and Chromatin Conference #EMBLTranscript here at @EMBL never fails to deliver. Truly inspiring talks and posters. Felt lucky to share and discuss our work with peers. Big thanks to the organizers EMBL Events !

Thrilled to share that our work from the Noh Lab EMBL is now published in its peer-reviewed form Nature Communications! 🥳🥳🥳 Curious how histone H3.3 K9 and K27 residues contribute to transcriptional regulation? Here's a sneak peek...🧵 (1/n) 📄rdcu.be/dSyQz #chromatin

EMBL Researchers & their collaborators discovered a process by which cells prevent the activation of ancient viral sequences in the genome. The study shows experimentally, for the first time, the causal role certain histone sites play in gene repression. embl.org/news/science-t…