Very interesting review in Nature Rev Endocrinol on putative endotypes in T1D. Endotypes indicate unique pathological processes that require specific treatments – are we indeed already able to define reliable endotypes of T1D? nature.com/articles/s4157…

New collaborative publication: "LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes". Congratulations to everyone involved! 🥳 FUNctional genetics of IMMUNE disorders onlinelibrary.wiley.com/doi/10.1002/ad…

New pre-print from the lab deposited at bioRxiv: biorxiv.org/cgi/content/sh… - it shows that Interferons are the key cytokines acting on pancreatic islets in type 1 diabetes.

Dos científicos de Cabimer Fundación Progreso y Salud, Benoit Gauthier y Nadia Cobo están en la ULB Center for Diabetes Research aprendiendo sobre organoides de islotes derivados de IPSC en el contexto de una ayuda de la JDRF Research. Gracias a Decio Eizirik y a Sandra Marin.

New collaborative publication from our Center: "A machine learning-based classification of adult-onset diabetes identifies patients at risk of liver-related complications". Check it out 👉🏻 jhep-reports.eu/article/S2589-…

New collaborative publication from our Center: "EndoC-bH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion". Congratulations to all the authors involved! sciencedirect.com/science/articl…

New publication from our Center: "Impact of saturated compared with unsaturated dietary fat on insulin sensitivity, pancreatic β-cell function and glucose tolerance: a systematic review and meta-analysis of randomized, controlled trials". Congratulations! sciencedirect.com/science/articl…

And another collaborative publication: "Inferring regulators of cell identity in the human adult pancreas". Check it out 👇🏼 ncbi.nlm.nih.gov/pmc/articles/P…

📢 Thursday 9/14 (9 am PT//12 pm EST) @JDRF American Diabetes Association nPOD Diabetes ULB Center for Diabetes Research Dr Mark Guthridge Munir Akkaya Dr. Deanna Santer Achille Broggi JDRF UK JDRF Canada Dr Peter A Senior Center for Diabetes and Metabolic Diseases Eli Lilly and Company Kalwat Lab Isabela Iessi ISLET Islet Biology Lab - UMH 📢 tinyurl.com/ttshbbbw

New collaborative publication! Check it out 👉🏻 "Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset" nature.com/articles/s4146….

And one collaborative pre-print: ncbi.nlm.nih.gov/pmc/articles/P… Congratulations to the authors involved!

New collaborative publication: "Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention". Check it out 👉🏻 link.springer.com/article/10.100…

RedRibbon: A new rank-rank hypergeometric overlap for gene and transcript expression signatures. It holds the promise to accurately extricate detailed information from large comparative analyses ULB Center for Diabetes Research life-science-alliance.org/content/7/2/e2…

New publication from our Center: "RedRibbon: A new rank–rank hypergeometric overlap for gene and transcript expression signatures". Congratulations to all the authors involved!!! life-science-alliance.org/content/7/2/e2…

New collaborative publication: "Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis". Congratulations to all the authors involved! biosignaling.biomedcentral.com/articles/10.11…

Our friend Alexandra and colleagues from ULB Center for Diabetes Research indicate a predominant role for the interferons, both IFN-α and IFN-γ, in the pathogenic response observed at the beta cell level in #type1diabetes as compared with a milder impact of IL-1β and TNF-α. link.springer.com/article/10.100…

New publication from our Center, with congratulations to all the authors involved! 🎉 "Interferons are key cytokines acting on pancreatic islets in type 1 diabetes". Check it out 👉🏻 link.springer.com/article/10.100…

New publication from our Center: "Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer's disease pathology progression". Congratulations to the authors involved! pubmed.ncbi.nlm.nih.gov/38833073/

And another collaborative publication! "PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2" pubmed.ncbi.nlm.nih.gov/38822524/

New publication by our Center in Diabetologia: "Comment on the role of interferons in the pathology of beta cell destruction in type 1 diabetes. Reply to Lenzen S [letter]". Congratulations to the authors involved! link.springer.com/article/10.100…