I’m delighted that the approved Mitomycin medac dose in the HIVEC-HEAT trial is 80 mg so that the recirculating concentration after priming external tubing is optimal - 1 mg/mL

Another milestone reached on the trial, we are now sending out Local Information Packs! If you have completed a feasibility form and are ready to receive LIP, please let us know if you haven't already #hivec Leyshon Griffiths Combat Medical #HIVEC #HIPEC

Medicine is difficult! Standing over my 46 years of clinical practice, I couldn't agree more... doi:10.1136/bmj.q2163 Thomas Dayspring Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 Pam R. Taub, MD❤️💃🏻 Biljana Parapid, MD, PhD, FESC Dr Amar Puttanna 🎸 Andrew J Sauer MD Erin D. Michos, M.D. SABOURETCardiologist Claudio Tinoco Mesquita Otavio Berwanger John Kastelein 👇🏽👇🏽

Embracing AI in medical education and clinical workflows - Harvard is leading the way.

A Systematic Review and Cost Effectiveness Analyses from the International Bladder Cancer Group for Therapies in BCG Unresponsive NMIBC sciencedirect.com/science/articl… David D'Andrea European Urology Oncology Morgan Roupret Alex Masson-Lecomte Shahrokh F. Shariat Paolo Gontero Hugh Mostafid IBCG

VentureVersity - bridging the gap between academia and business

🧪Patients across the country will benefit from cutting-edge treatments and clinical trials. 🔬£100 million of public-private investment will fund 20 new clinical research hubs similar to @PRCLeicester. Learn more: gov.uk/government/new… National Institute for Health and Care Research Leicester's Hospitals

The special focus in this national report is priorities for patient safety in the UK.

How do we make sense of two “negative” trials in NEJM and a “positive” meta-analysis of the two trials in NEJM Evidence? Emil Hodzic-Santor and Michael Fralick share some insights in this editorial: eviden.cc/3OYutgJ

Big news👋. A positive R3 trial for PD-1 in NMIBC! The CREST trial evaluated sasanlimab (PD-1i)+BCG vs Standard BCG (induction and maintenance) in BCG-naïve, high-risk NMIBC.The study met its primary endpoint of EFS with ‘clinically meaningful’ results. pfizer.com/news/press-rel…

Future of England’s medical apprenticeships is in doubt as pilot schemes are put on hold | The BMJ bmj.com/content/387/bm…

Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC… Journal of Clinical Oncology ASCO Nick James also on @Prof-Nick-James.bsky.social

Our editorial on the #BladderPath study: Could MRI-first staging streamline MIBC treatment? Skipping TURBT may reduce delays—especially for those needing palliative care or radiotherapy. Journal of Clinical Oncology Andrea Necchi jim catto Nick James also on @Prof-Nick-James.bsky.social #OncSurgery #BladderCancer

Fast approaching recruiting our first participant, we now have 2 Site Investigator Visits booked with The Royal Wolverhampton NHS Trust 🏥 and Worcestershire Acute Hospitals NHS Trust R&I 🥳 Check out our newsletter for further updates including our brand new wonderful Senior Trial Manager. Welcome Emma! Leyshon Griffiths Combat Medical #HIVEC #HIPEC

Can we identify IR-NMIBC patients who can safely undergo Active Surveillance ? #EAU25 We (Wei Shen Tan Roberto Contieri) investigated AS in IR-NMIBC using IBCG risk factors and found: 🔹 Patients with 0 IBCG risk factors were over twice as likely to remain on AS compared to those

Bladder-sparing strategies for BCG- unresponsive NMIBC - Cost and patient selection are challenges

The HIVEC HEAT trial will be featured at the Combat Medical #HIVEC #HIPEC stand at the BAUS conference next week in Manchester. Come by and chat with Leyshon Griffiths, Leyshon Griffiths, our Chief Investigator, next Tuesday to learn more. Leicester Clinical Trials Unit #HIVECHEAT

We are back, and have been working behind the scenes. We can finally announce that we have officially opened our first HIVEC-HEAT site. A warm welcome to Worcestershire Acute NHS Worcestershire Acute Hospitals NHS Trust R&I Combat Medical #HIVEC #HIPEC Leicester Clinical Trials Unit Leyshon Griffiths

Happy Friday We have wonderful news to end the week on. We have officially opened our 4th site for the trial. Welcome to the team at Imperial College Healthcare NHS Trust to HIVEC-HEAT. We look forward to working with you 🥳 Leicester Clinical Trials Unit Leyshon Griffiths Combat Medical #HIVEC #HIPEC

Happy Friday everyone. Here is Octobers Newsletter. A celebration of Black History Month, site updates and how to contact us to get your site involved in HIVEC-HEAT Trial. Have a lovely weekend. #TGIF #HIVECHEAT #HIVECHEATTRIAL Combat Medical #HIVEC #HIPEC Leicester Clinical Trials Unit