📢 Excited to share our new paper out today in Nature Neuroscience! 🧠✨ We uncover how compartmentalized dendritic plasticity in the retrosplenial cortex (RSC) links contextual memories formed close in time. A thread 🧵👇 [1/8] nature.com/articles/s4159…

New from the lab!! 👉🏼authors.elsevier.com/a/1kgT43BtfHCz… 📝Neuron We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Julio Esparza Juan Pablo Quintanilla Juan Álvaro Gallego

Very proud of this new preprint of a study by Conor Dorian and co-led by Golshani and Buonamano labs. We find that hippocampal neurons can encode both working memory and implicit timing. biorxiv.org/content/10.110…

Thrilled to share this study is now out - thanks to the thoughtful and constructive reviewers for strengthening the paper! And huge congrats to first author Dr. Celine Drieu and amazing team of Ziyi Zhu sarah elnozahy, joy wang, Aaron Wang, and Kylie Fuller rdcu.be/eeeBa

New hope for families battling Dravet Syndrome. Scientists have developed a new gene replacement therapy that could improve treatments for a rare and life-altering form of epilepsy. 🧵

Our latest research, led by Antoine Madar, on what #SynapticPlasticity rules shape CA1 and CA3 representations in the hippocampus during familiarization has just been published in Nature Neuroscience! Read here: nature.com/articles/s4159…

We are recruiting a postdoc - if you are looking for the next step after finishing your PhD, and interested in interneurons and epilepsy, check out our website: dudoklab.com/careers

At #Cosyne2025? Come by my poster today (47) to hear how sequential predictive learning produces a continuous neural manifold that can generate replay during sleep, and spatial representations that "sweep" ahead to future positions. All from sensory information + action!

Excited to share our new study: "Cold memories control whole-body thermoregulatory responses" by Andrea Muñoz Zamora, Aaron Douglas & team at Trinity College Dublin, in collaboration with Lydia Lynch & Christine Ann Denny Ryan Lab nature nature.com/articles/s4158…

I’m excited to share a new paper from the lab. The study led by Xiaowei Gu reveals how the mPFC encodes complex emotional memories, using an internal model to infer emotional associations and memories via projections to the amygdala rdcu.be/el19t nature.com/articles/s4158…

Dendritic inhibition terminates plateau potentials in CA1 pyramidal neurons First preprint from the lab! Wonderful team effort, lead by incredibly talented Lee Vaasjo (Lee O Vaasjo, PhD) and Shawn Kotermanski biorxiv.org/content/10.110…

"Contribution of perineuronal nets to hyperexcitability in pilocarpine-induced status epilepticus" is now out in Epilepsia! 🤔What's in it, you ask? We found interneurons in the mouse hippocampus develop new matrix structures called perineuronal nets after undergoing... (1/4)

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope! Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals. Read the paper here: science.org/doi/10.1126/sc… (1/9)

My final postdoc paper from the Golshani lab is finally out! How does inhibition regulate memory-encoding pyramidal sequences? We used kHz-rate voltage imaging of mouse CA1 PV & SST cells during a working memory task with odors. nature.com/articles/s4159…

Memory researchers in New York, check this out 👇 I'm so excited for this conference! It's going to be a fantastic day of collaborative learning and discussion about all things memory 🧠

In these difficult times (all grants frozen) it is good to recognize the good that science can do. Very proud of our new paper on open-source 2P miniscopes! They can image dendrites in cortex and dentate granule neurons through an intact CA1. nature.com/articles/s4146…

Excited for MCCS this year! Join us in November 🤓🧠

Thank you to all of the speakers who will be joining us for the first annual New York Memory Hub conference in September! It's going to be a fantastic day! Register now 👇

🎨 Not only are we excellent scientists, but it looks like we're also quite talented artists, too! Had a blast hanging out and painting with the Cai and Shuman Labs 🖌️