Tristan Shuman
@tristanshuman
Neuroscientist studying circuit dysfunction in epilepsy and Alzheimer's disease. Assistant Professor at Icahn School of Medicine at Mount Sinai. he/him
ID: 23245919
http://labs.neuroscience.mssm.edu/project/shuman-lab/ 07-03-2009 23:02:43
1,1K Tweet
2,2K Followers
1,1K Following
Gene editing of APP C-terminus rescues neuropathology, ephys, behavior, and transcriptomic changes in #alzheimer knockin mice. Led by Brent Aulston, collaboration with labs of Krishanu Saha Mark Zylka Marcelo Wood Jon Audhya (Madison) #crispr #therapeutics biorxiv.org/content/10.110…
If you think that this work is exciting we have postdoc and RA positions in the Rudebeck Lab, Helen Mayberg, MD and Brian Russ labs to work on the neural basis of DBS. Friedman Brain Institute
It's out ‼️ 📢 Check out my PhD work with Kevin Bath! We find that early life adversity in mice disrupts central amygdala CRF+ neuron activity, augmenting the startle reflex in response to threat. doi.org/10.1038/s41467…
**Hot off the press!** 📰 Our inaugural preprint from the ChronoEpilepsyLab lab explores the dynamic link between circadian rhythms and epileptogenesis. Check it out! 🌟 #EpilepsyResearch RCSI RCSI School of Pharmacy and Biomolecular Sciences FutureNeuro Centre biorxiv.org/content/10.110…
Exciting news! I’ll be giving a special seminar Friedman Brain Institute. This is a place I’ve long wanted to visit, renowned for its incredible community of leading scientists. Deeply honored to have this opportunity. Thanks Tristan Shuman & Denise J. Cai, Ph.D. for hosting. Looking forward to it!
📢The latest from talented Saman Abbaspoor 's PhD is out in @cellreports! You into ensembles (Diagnostic Biochips DA or #neuropixels in #nhp)? ❤️CA1 microcircuits? Wonder why we don’t know how they support #memory or behavior in #primates? Like inhibitory cell types? Cell Assemblies in😴?
Check out our latest paper. Here we attempted to bridge levels of analysis in memory research, linking receptors, dendritic spines, higher-order neuronal dynamics and behavior in mice. Nature Neuroscience rdcu.be/dOjCK 1/
Extremely proud to showcase 170+ pieces of research driven by #opensource tools from the Miniscope Team! Dive into our interactive list of publications here: aharoni-lab.com/Impact/.🔍📘 Did we missed your work? We'd love to add it!
Exciting times for voltage imaging! In a new study published today, our collaborators Attila Losonczy and Adrian Negrean find that behavior regulates electrical signals in neuronal dendrites in a structured but dynamic way. nature.com/articles/s4146…
Seizures are unpredictable but don’t occur completely randomly. Here together with Arian Ashourvan we reconstruct the cyclical patterns that drive seizure risk, based on epileptiform activity recorded in individual patients over several months and years. biorxiv.org/content/10.110…
A new paper from our lab: Dentate gyrus ensembles gate context-dependent neural states and memory retrieval | Science Advances science.org/doi/10.1126/sc… This work was led by Cesar Coelho (postdoc in my lab) and Andrew Mocle (postdoc in Sheena Josselyn lab). A brief 🧵. 1/n
Absolutely ecstatic to be joining this group of fellows! I am already completely overwhelmed by the incredible and varied career and professional development support Simons Foundation and the Simons Collab on Plasticity and the Aging Brain cohort have provided. So excited for these next steps!
I’m thrilled to share our paper published online today in Science Magazine ! I appreciate my mentor, Dr.Fujisawa, for running through this project with me. We discovered the new type of grid cells that have grid field for future projected locations. science.org/doi/10.1126/sc…
Congrats to Zoé Christenson Wick, PhD on receiving a Simons Foundation Independence Award! So well deserved, and a truly great program to help her transition to independence.
Very proud of this new preprint by Conor Dorian and Jiannis Taxidis showing behavioral time scale plasticity is not limited to the spatial domain but can also new create new fields representing sensory stimuli, time &outcome during working memory performance. biorxiv.org/cgi/content/sh…
I’m excited to share an awesome new study from Jacqueline Garcia (an amazing grad student and #DSPAN scholar!!!) using GluSnFR imaging after TBI. She found specific spatiotemporal changes in glutamate that can guide our therapeutic strategies. biorxiv.org/content/10.110…
New lab paper alert! Work by Kelsey Lucerne, PhD and colleagues finds the cytokine CSF2 is increased by cocaine in a microbiome dependent manner. Increased CSF2 signaling leads to decreased cocaine preference and altered transcriptional response to cocaine. pubmed.ncbi.nlm.nih.gov/39098439/
