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New Witte Lab paper from PhD student Taylor Cavazos on improving transferability of polygenic risk scores. johnwitte UC San Francisco

Great video and blog post by @Linda_Kachuri explaining results from our recent paper showing how PRS improve cancer risk prediction. Watch it here and read the story behind the paper: go.nature.com/2XyMPu1 johnwitte Mattias Johansson

Mark your calendar for our first Inside Human Genetics and Genomics Advances on January 26 at 12 PM Eastern as johnwitte and Taylor Cavazos discuss their paper, "Improving Transferability of Polygenic Risk Scores." Register now. bit.ly/38Ce8dm

Grateful for the opportunity to share my recent work through the ASHG Journal Club! Register below to attend. 👇 Human Genetics and Genomics Advances Graduate Education and Postdoctoral Affairs UCSF Epidemiology & Biostatistics Witte Lab

Be sure to register for our upcoming journal club featuring johnwitte & Taylor Cavazos!

New paper by Witte Lab alum Arun Majumdar develops a more powerful two-step approach to detect GxE interactions across multiple traits. Bogdan Pasaniuc johnwitte academic.oup.com/bioinformatics…

Arun's on twitter at Arunabha Majumdar

Don't miss out on our first ever Human Genetics and Genomics Advances Journal Club, "Improving Transferability of Polygenic Risk Scores" tomorrow at 12 PM Eastern! johnwitte and Taylor Cavazos will discuss their paper before taking questions from the audience. bit.ly/3i7SQaP

Today in Nature Communications: "patterns of pleiotropy that have the potential to inform investigations of risk prediction, shared etiology, & precision #cancerprevention strategies." lori sakoda Kaiser Permanente Research NorCal KPNorthernCal @RebeccaEGraff johnwitte Witte Lab #cancer Study: ibit.ly/05q8

Exciting findings from Witte Lab collaboration with Kaiser Permanente Research NorCal led by @RebeccaEGraff shows cross-phenotype PRS effects may enable a more integrated model of cancer risk prediction, and inform new strategies toward reducing the burden of cancer. lori sakoda johnwitte Taylor Cavazos

New Witte Lab paper on cfDNA in prostate cancer by Emmalyn Chen, johnwitte, Felix Feng. While cfDNA concentration predicts mets, it has limited diagnostic ability for localized dx. But fragment size may distinguish localized dx. rdcu.be/cgdyB. UCSF Epidemiology & Biostatistics

Congratulations to Erin Gilbertson for receiving an NSF Honorable Mention! This is a significant national academic achievement and we UC San Francisco are proud of Erin.

New Witte Lab study led by Nima Emami PHD and Taylor Cavazos finds novel loci and genes associated with prostate cancer in over 200,000 men from UK Biobank and Kaiser Permanente Research NorCal. UCSFUrology johnwitte bit.ly/3ulemh9

New Witte Lab paper on cfDNA in prostate cancer by Emmalyn Chen (happy birthday!), Clint Cario , Carroll, Peter et al. Targeted cfDNA sequencing can detect somatic tissue alterations in heterogeneous, localized disease. ascopubs.org/doi/full/10.12… UCSF Epidemiology & Biostatistics UCSF Helen Diller Family Comprehensive Cancer Ctr

Dr Rebecca Graff @RebeccaEGraff joined our faculty UCSF Epidemiology & Biostatistics after her postdoc with Witte Lab She’s a cancer genetics epidemiologist with a focus on prostate cancer & PCF Science 2020 Young Investigator awardee! More here: profiles.ucsf.edu/rebecca.graff

We ❤️ postdocs UCSF Epidemiology & Biostatistics Postdocs@UCSF Meet Dr Jovia Nierenberg Jovia Nierenberg working with Witte Lab & Dr Elad Ziv profiles.ucsf.edu/jovia.nierenbe… Human genetics & Disease risk (and cool prior work on hypertension)!

#ASHG21: Excited to share our work on #cancer #genetics of multiple primary tumors in two large cohorts tomorrow (10/19) at 11:45am EDT! #PrgmNr1015 Big thanks to our collaborators at Kaiser Permanente Research NorCal and Regeneron Genetics Center. @johnwitte Witte Lab UCSF Helen Diller Family Comprehensive Cancer Ctr bit.ly/3G8JGGH

New! Genomic analyses from Jiang et al. suggest that genetics could help guide clinical management of #prostate cancer #OA johnwitte Witte Lab bit.ly/3qX9gsO

The last chapter of my thesis on genetic risk factors for developing multiple primary tumors is now on medRxiv! Through #WES data from UK Biobank and Kaiser Permanente Research NorCal, we identify potential pleiotropic variation in individuals with multiple cancers. John Witte lori sakoda

Genetic adjustment of PSA values may reduce unnecessary testing and increase the detection of aggressive #ProstateCancer tumors, according to research presented at #AACR22 Read more here: bit.ly/3jCtwem #MedNews UC San Francisco UCSF Helen Diller Family Comprehensive Cancer Ctr @Linda_Kachuri