Vaclav Veverka (@vaclav_veverka) 's Twitter Profile
Vaclav Veverka

@vaclav_veverka

scientist, structural biologist, senior PI (@IOCBioNMR) at @IOCBPrague and @CharlesUniPRG

ID: 174639123

calendar_today04-08-2010 12:41:48

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IOCB Prague (@iocbprague) 's Twitter Profile Photo

The structure of SARS-CoV-2 nucleocapsid phosphoprotein in complex with RNA, published by Vaclav Veverka, Evžen Bouřa, and their teams IOCB Prague, was highlighted as the RCSB PDB rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 Molecule of the Month, drawn by David Goodsell. pdb101.rcsb.org/motm/278

The structure of SARS-CoV-2 nucleocapsid phosphoprotein in complex with RNA, published by <a href="/vaclav_veverka/">Vaclav Veverka</a>, Evžen Bouřa, and their teams <a href="/IOCBPrague/">IOCB Prague</a>, was highlighted as the RCSB PDB <a href="/buildmodels/">rcsb pdb 💉🧬💻🔬💊🌱🧠🦠</a> Molecule of the Month, drawn by David Goodsell.

pdb101.rcsb.org/motm/278
H. Courtney Hodges (@hodgeshc) 's Twitter Profile Photo

Why do #transcription regulators contain so many IDRs? Do #IDRs generate selective interactions or just make droplets? Are there different "types" or a "grammar" of disordered protein? Katerina Cermakova, cermakova.bsky.social takes on these questions and many more in our new review cell.com/trends/biochem…

Katerina Cermakova, cermakova.bsky.social (@katacermaku) 's Twitter Profile Photo

In our review with Vaclav Veverka and H. Courtney Hodges, we dive into TFIIS N-terminal domains (TNDs), which "read" #IDRs called TIMs. How do TNDs and TIMs influence #transcription? Regulated proximity impacts major regulators -- and important TFs like MYC! portlandpress.com/biochemsoctran…

In our review with <a href="/vaclav_veverka/">Vaclav Veverka</a> and <a href="/hodgeshc/">H. Courtney Hodges</a>, we dive into TFIIS N-terminal domains (TNDs), which "read" #IDRs called TIMs. How do TNDs and TIMs influence #transcription? Regulated proximity impacts major regulators -- and important TFs like MYC! portlandpress.com/biochemsoctran…
IOCB Prague (@iocbprague) 's Twitter Profile Photo

#IOCBInvitedLecture 2023 Next Monday, 20 February, 10 a.m. we are hosting Prof. Eva Nogales (UC Berkeley) with an invited lecture Structural Insights into the Regulation of the Gene Silencer PRC2. All interested students and researchers are welcome. uochb.cz/en/event-calen…

Vaclav Veverka (@vaclav_veverka) 's Twitter Profile Photo

We are looking for a PhD student to join our lab at IOCB Prague to study chromatin associated complexes. #structuralbiology #nmr #cryoem #transcription #epigenetics @iocbionmr uochb.cz/en/open-positi… instagram.com/p/ChsE3UfDw2C/…

Shasha Chong (@schong_ustc) 's Twitter Profile Photo

My lab Caltech Chemistry & Chemical Engineering is #hiring! Looking for a postdoc to join us in sunny Pasadena and tackle questions related to IDPs, phase separation, and transcriptional control using diverse experimental approaches. Please RT. Details and how to apply: nature.com/naturecareers/… #jobs

The EMBO Journal (@embojournal) 's Twitter Profile Photo

Extensive multivalent interactions between #BRCA1/#BARD1 E3 ligase IDRs & #nucleosome substrates facilitate chromatin recruitment & contribute to histone H2A ubiquitylation and to DNA repair Sam Witus et al Klevit Lab UW Biochemistry Zhao Lab UT Health San Antonio embopress.org/doi/10.15252/e…

Extensive multivalent interactions between #BRCA1/#BARD1 E3 ligase IDRs &amp; #nucleosome substrates facilitate chromatin recruitment &amp; contribute to histone H2A ubiquitylation and to DNA repair
<a href="/SamWitus/">Sam Witus</a> et al <a href="/KlevitLab/">Klevit Lab</a> <a href="/UWBiochemistry/">UW Biochemistry</a> <a href="/WXZhaoLab/">Zhao Lab</a> <a href="/UTHealthSA/">UT Health San Antonio</a>
embopress.org/doi/10.15252/e…
Philip Ball (@philipcball) 's Twitter Profile Photo

Fantastic review of how intrinsically disordered proteins do their many jobs in the cell. If you like this kind of thing, you'll like this! nature.com/articles/s4158…

Katerina Cermakova, cermakova.bsky.social (@katacermaku) 's Twitter Profile Photo

For the first time, we find a common mechanism for SWI/SNF addiction in cancer. Our paper reveals that G1 phase is a critical moment for SWI/SNF activity in several addicted cancers, including neuroblastoma, AML, prostate cancer, and uveal melanoma academic.oup.com/nar/advance-ar… (1/6)

For the first time, we find a common mechanism for SWI/SNF addiction in cancer. Our paper reveals that G1 phase is a critical moment for SWI/SNF activity in several addicted cancers, including neuroblastoma, AML, prostate cancer, and uveal melanoma academic.oup.com/nar/advance-ar… (1/6)
H. Courtney Hodges (@hodgeshc) 's Twitter Profile Photo

What do SWI/SNF-addicted cancers have in common? And when are they most sensitive to SWI/SNF inhibition? Check out Katka’s Tweetorial highlighting our most recent paper

Rémi Buisson (@remibuisson) 's Twitter Profile Photo

Now online! APOBEC3A and APOBEC3B drive distinct mutational landscapes in tumors. We showed how A3A and A3B substrate preferences for different hairpin structures can be exploited to identify patients' tumors with mutations caused by either A3A or A3B. nature.com/articles/s4146…

Vaclav Veverka (@vaclav_veverka) 's Twitter Profile Photo

Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers academic.oup.com/nar/article/do…

Tim Fenton (@timfenton10) 's Twitter Profile Photo

New pre-print! This one's been a long time in the works and we're excited to share it... Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus biorxiv.org/content/10.110…

Pétur Heidarsson (@heidarsson_lab) 's Twitter Profile Photo

Exciting news! I am grateful and thrilled to join the Section for Biomolecular Sciences #UCPH. We use single-molecule tools to study how pioneer factors interact with chromatin and promote cell reprogramming. Join our ERC-project PIONEER, now recruiting on all levels!⬇️

Exciting news! I am grateful and thrilled to join the Section for Biomolecular Sciences #UCPH. We use single-molecule tools to study how pioneer factors interact with chromatin and promote cell reprogramming. Join our ERC-project PIONEER, now recruiting on all levels!⬇️
Nucleic Acids Res (@nar_open) 's Twitter Profile Photo

Tracking live-cell single-molecule dynamics enables measurements of heterochromatin-associated protein–protein interactions doi.org/10.1093/nar/gk…

Tracking live-cell single-molecule dynamics enables measurements of heterochromatin-associated protein–protein interactions doi.org/10.1093/nar/gk…