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Q: if monoclonal antibodies for Alzheimer's were available now, how many people in the UK would be eligible? A: 30,200 people/yr (less than expected) applying trial criteria to real populations in Cambridge + South London. Read our paper here ⬇️ bit.ly/addemand

Please see our preprint here: biorxiv.org/content/10.110…

As part of #WorldAlzheimersMonth, we spoke to Marc Aurel Busche, Group Leader at UK Dementia Research Institute about his research, which he hopes will aid in the development of Alzheimer's disease treatments that are both safer and more effective: bit.ly/4cZWhes #UCLDementia

Our new paper shows #psilocybin has similar long-term antidepressant effects as the #SSRI escitalopram but leads to greater improvements in psychosocial functioning, connectedness, and life meaning. Published in Lancet @EClinMedicine. thelancet.com/journals/eclin… 🧵1/10

New unit paper by McHugh et al. from Dupret group provides novel insights into a type of neural activity that helps nerve cells work together during sleep for making new, adaptable memories, published in Neuron! mrcbndu.ox.ac.uk/publications/o… Nuffield Department of Clinical Neurosciences University of Oxford

Temporal structure of experience etched on firing of human hippocampal-entorhinal neurons to serve memory & prediction. See our study nature at UCLA Neurosurgery 🧠, great work by lead author Pawel Tacikowski with Guldamla Kalender & Davide Ciliberti support NINDS. nature.com/articles/s4158…

Interested in the utility of EEG for early / differential diagnosis of dementia? Check out latest preprint from our unit (tinyurl.com/22xrzaz4): medrxiv.org/content/10.110…

Hippocampal ripples during offline periods predict human motor sequence learning. Work led by the brilliant @PinChun_Chen. biorxiv.org/content/10.110…

Why academia is sleepwalking into self-destruction. My editorial Brain If you agree with the sentiments please RT. It's important for all our sakes to stop the madness academic.oup.com/brain/issue/14…

Excited to share our preprint led by Ain Chung & Jason Alipio showing how few immature adult-born DGCs preferentially recruit inhibition of CA2 and CA3 to disproportionately affect hippocampal network properties and social memory. We began by asking 1/n biorxiv.org/content/10.110…

Im pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, now out in Cell Reports! With Demi Brizee & David Dupret, we track how rhythms and spiking behavior map onto hippocampal layers. doi.org/10.1016/j.celr…