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🆕️⚡️⚡️ Open Forum Infectious Diseases Ryan Shields Epidemiology & Clinical Outcomes of non-HACEK Gram-negative Infective Endocarditis This is the first study to identify Serratia spp. as the most common etiology of GNIE, which was particularly true among PWID #IDTwitter academic.oup.com/ofid/advance-a…

In the largest study of gram-negative endocarditis to date, we found Serratia to be most common. If there is benefit to combination therapy, it may depend on the pathogen. Open Forum Infectious Diseases academic.oup.com/ofid/advance-a…

Since guidelines for antibiotic prophylaxis in Endoscopic endonasal surgery have not been developed, we looked at the pathogens causing post operative CNS infections following this procedure at our program. We also found another use for MRSA nares swabs. sciencedirect.com/science/articl…

In our study of patients with a FQ allergy and administration of a different fluoroquinolone, we found the reaction risk occurred with a challenge to moxifloxacin (2/19; 9.5%), followed by ciprofloxacin (6/89; 6.3%), and levofloxacin (1/44; 2.2%). journals.asm.org/eprint/4MT2WWC…

Amphotericin B has been recommended for Malassezia bloodstream infections. However, we took a look at our cases and found posaconazole may be a reasonable substitute. sciencedirect.com/science/articl…

“This case series is in alignment with previous studies that suggest low risk of cross-reactivity between fluoroquinolones” Read the article by Adams & Shah: doi.org/10.1093/jac/dk… #JACNews

The largest series of Serratia endocarditis to date! 🆕️⚡️#JAC Sunish Shah Serratia endocarditis: antimicrobial management strategies and clinical outcomes Combination antibiotic treatment was associated with improved outcomes #IDXposts #IEWiki academic.oup.com/jac/article-ab…

#idtwitter If you had a 35 year old PWID with a 2 cm TV vegetation /pulmonary emboli due to mssa that is failing to clear blood cultures after 5 days of cefazolin, what would you do? Madeline King-Patel Gabe 🦊 B. Smith have thought about this so I hope they don’t mind my tags

🏥#MedTwitter...COMING Mon, 10/30 📝How to best use Paxlovid in Outpt setting w/⭐️Natasha Bhuyan, MD, FAAFP & Me + Bonum CE Supported by an edu grant from Pfizer Inc. 🟢Answer PRE-polls👇 🗓️Watch video Mon 🔴Answer post-polls 🏆Claim 🆓 #CME👉bit.ly/sim-pax 1⃣st: Tell us who u are

🆕#Breakpoints Episode: Drs. Nicolas Torney & Sunish Shah join Dr. Jeannette Bouchard (@jlbouchard001) to discuss our next topic in our Dosing Consult series: BID vs TID dosing for metronidazole. Dive ➡️PK/PD & real-world application of this switch! 🎧 sidp.pinecast.co

🆕️⚡️⚡️ Clinical Infectious Diseases Rates of resistance to ceftazidime-avibactam and ceftolozane-tazobactam among patients treated for multidrug-resistant Pseudomonas aeruginosa bacteremia or pneumonia #idxposts academic.oup.com/cid/article/do…

Among patients with MDR PSAR bacteremia or pneumonia, we found a higher rate of treatment emergent resistance due to ceftazidime avibactam compared to ceftolozane tazobactam academic.oup.com/cid/advance-ar…

academic.oup.com/jac/advance-ar… ^here was the answer (kinda/sorta)

🆕️🔥Multicentre, retrospective study #JAC Sunish Shah Ryan Shields Carbapenem *+ cefaz or ASPs resulted in faster time to blood culture sterilization,but NO DIFFERENCES in overall MORTALITY rates in patients with persistent MSSA bacteraemia [>48 h] academic.oup.com/jac/article-ab…

The largest study of Pseudomonas endocarditis to date 🆕️🔥#JAC Sunish Shah Ryan Shields Clinical manifestations and treatment outcomes for patients with Pseudomonas endocarditis Combination therapy did not improve clinical outcomes #IDXposts #IEwiki academic.oup.com/jac/article-ab…

Carbapenem combination resulted in faster blood culture sterilization for MSSA by 25 h compared to matched controls, but no differences in mortality: doi.org/10.1093/jac/dk… Sunish Shah Ryan Shields @OUPMedicine Oxford Journals #JACNews

🆕️⚡️⚡️Retrospective Study #AAC Real world data Incidence of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents #IDXpost Linezolid vs. Tedizolid? journals.asm.org/doi/10.1128/aa…

🆕️✨️The largest study to date of patients with Bacteroides spp. Bacteremia Metronidazole 500mg q12h dosing was not associated with worse outcomes compared to metronidazole 500mgq8h 500mgq12h works for bactremia. It works for other infections, too sciencedirect.com/science/articl…

You can dose metronidazole at 500 mg every 12 hours based on this analysis of 242 patients with Bacteroides bacteremia It took us 6 years to finish so give it a read! sciencedirect.com/science/articl…

Our last virtual open house for our PGY2 in ID at YNHH of the recruitment season is this Wed. (12/18)! Use the link below to register and learn more about our great hospital and amazing program!! 🤓💊🧫 #ynhhspharmacy #idpharmd #pharmacyresidency #pgy2 #pharmacyx #MedTwitter