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New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging! We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking. biorxiv.org/content/10.110…

The actin #cortex is attached to the #membrane via linking proteins. When these linkers get trapped in the cortex meshes, actin jams🚧, #contractility stops🛑 and cells polarise☄️Exciting collaboration (+ real fun!) with Diz-Muñoz Lab Rubén Tesoro Moreno Andela Saric 📑biorxiv.org/content/10.110…

Apply! 📝

A great 🇬🇧-🇦🇹team of Billie Meadowcroft (currently cycling 🚴‍♀️ across 🇺🇸) Ivan Palaia Valerio Sorichetti and Eryk teamed up with with Nargess Khalilgharibi and Yanlan Mao to simulate collagen-iv remodelling under strain and enzymatic activity. ISTAustria UCL Laboratory for Molecular Cell Biology UCL IPLS More ⬇️

Did you know there are more than bilayer #membranes in nature? Meet the #archaeal monolayer and its surprising mechanical properties! New #preprint! (1/7)

Taken together, we find membrane tradeoff design principles evolved in extremophiles - stability vs reshapeability - that can be valuable for (bio)technological applications. (7/7) 🙏 Felix Frey , XIUYUN JIANG , Buzz Baum Andela Saric preprint → doi.org/10.1101/2024.1…

Archeal monolayer membrane properties. Interesting work from Andela Saric. Are there implications for origin of life? biorxiv.org/content/10.110…

We're hiring for a MSCA PhD position! ComeInCell We're curious about how biological condensates can be actively targeted to membrane surfaces with the thoroughly mastered self-assembling protein machinery. Check out the project at comeincell.org/dc03-active-sp…

The ITN ComeInCell 🧫comeincell.org is UP sand running! Interested in synthesizing life-like systems from the bottom up? 🔊Apply now to the 2 PhD positions that we offer @ciqus within an outstanding network!! RT is highly appreciated! ⏰👉 usc.es/ciqus/es/forma…

We're super excited to launch ComeInCell- a doctoral network aimed to develop advanced cellular mimics that integrate functional membrane structures and biomolecular condensates. With a team of 14 PIs and 13 associated partners, this will be an exciting journey!

📢 Open PhD position as part of #MSCA network of 17 students ComeInCell Interested in exploring membrane stability/repair & #condensates ? Check out & apply: 👉bit.ly/4fd8HRU The project will include secondments at Andela Saric, Carlos Marques & Nature Communications

Registration is open for the 2025 iteration of the wonderful EMBO Events workshop on cell polarity and membrane dynamics #EMBOcellPolarity25 I am organizing with Ed Munro! Wonderful lineup wonderful please sign up and RT meetings.embo.org/event/25-cell-…

🤩 Exciting milestone for the #MSCA Doctoral Network #ComeInCell! Today we held our kickoff meeting to drive this groundbreaking project forward. Stay tuned for insights into #SyntheticBiology, #MembraneCondensates, #NeurodegenerativeDiseases, #MembraneTrafficking & more! 🔬✨

Congratulations to Anđela Šarić Andela Saric on being named an Allen Distinguished Investigator by Paul G. Allen Family Foundation! She will lead an international collaboration, funded with $1.5 million, to investigate how chemically active membranes influence cell shape. 🔗 bit.ly/3B65vJc

Thank you Allen Institute for seeing the magic in #membranebiophysics 🪄✨ We’re thrilled happy to be a part of this cohort!

New edition of Interdisciplinary challenges (IntCha25) on physics of complexity and life will take place at Heidelberg in 2025 embl.org/about/info/cou… EMBL So proud the event keeps gathering ECR for rich exchanges Davide Michieletto ready for the 10th anniversaire? Previous Editions👇

Are you a fan of #ComputationalBiophysics?🖥️ The Andela Saric at the #ISTA is seeking a talented #PhDcandidate to investigate the fascinating interplay between #MolecularCondensates and #CellMembranes. Check our #PhDposition: comeincell.org/dc12-in-silico… #MSCA #ComeInCell