🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

SCANZ Crystal35 continue in the afternoon, with 2 sessions ;-) Pleasure to hear from Begona Heras Megan Maher Rhys Grinter and David Jacques Then time to catch up with friends for dinner ♥️

1 in 3 big corporations pay no tax. We can raise $514 billion if we tax them fairly. Free and unlimited mental healthcare is more than possible. All we need is the political will.

Shut up please.. Israel has the right to self-defence.

PM Session has commenced with Dr. Felix Bennetts Monash Institute of Pharmaceutical Sciences with his presentation on "Decoding the P2X1 receptor structural insights and drug development" 👏 Bio21 Institute WEHI (Walter and Eliza Hall Institute) Molecular Horizons @ UOW Australian Research Council

Day 2 of the #CCeMMP Symposium has begun with our industry speaker Dr. Nie Xin Thermo Fisher sharing insights into "New advances in cryo-electron microscopy: from basic research to translational science" 🙌 Monash Institute of Pharmaceutical Sciences WEHI (Walter and Eliza Hall Institute) Bio21 Institute Molecular Horizons @ UOW Australian Research Council

The next presenter is Rhys Grinter Bio21 Institute showcasing his research on "Inhibiting bacteria heme-piracy using de novo designed proteins" 👏 Monash Institute of Pharmaceutical Sciences WEHI (Walter and Eliza Hall Institute) Molecular Horizons @ UOW Australian Research Council

Final speaker for our AM session is Mahmuda Yeasmin Monash Institute of Pharmaceutical Sciences presenting "Structural basis of the clinical candidates at muscarinic acetylcholine receptors" 👏 Bio21 Institute Molecular Horizons @ UOW WEHI (Walter and Eliza Hall Institute) Australian Research Council

Our experience with #alphafold3 🤖 (code recently released) and some of our most recent #cryoEM 🔬 structures (thread below) nature.com/articles/s4158… nature.com/articles/s4146…

As Lorne Protein Meeting approaches its 50th anniversary we’re excited to highlight the fantastic speakers coming in 2025 to celebrate. lorneproteins.org/speakers2025

Absolutely thrilled that our ARC #DP25 was funded 🥹 I'm so proud of our team of talented #womeninSTEM - Dr Lesley Cheng and Emily Mackie 🙌🏻 Thank you to the College of Experts, assessors, mentors and my amazing team Uni of Adelaide! Can't wait to get this project started 🎉🌱

De novo design of potent CRISPR-Cas13 inhibitors 1. Introducing AIcrs: A novel approach using AI-driven de novo protein design to create potent anti-CRISPR inhibitors, targeting CRISPR-Cas13 systems. These AI-designed inhibitors (AIcrs) offer unprecedented specificity and

The Knott lab

We are excited to share pre-prints describing a successful foray into ML-driven protein design. With Rhys Grinter we designed proteins to potently inhibit CRISPR-Cas13 (doi.org/10.1101/2024.1…) or block heme piracy by pathogenic E. coli (doi.org/10.1101/2024.1…):

Excited to share my first-author preprint as part of the Gavin Knott Lab! Using de novo protein design, we developed anti-CRISPRs to potently inhibit CRISPR-Cas13. Huge thanks to my amazing co-authors ! #CRISPR biorxiv.org/content/10.110…

Thrilled to see our work on high-resolution #cryoem using a common LaB6 120-keV TEM and sub–200-keV direct electron detector, now online Science Advances. science.org/doi/10.1126/sc… . A collaboration with Gatan Microscopy, @GeorgRamm, and Ramaciotti Centre for Cryo EM.

👀📅👇One week left to apply for this fully-funded UK PhD - closing date 3rd February. Come and join my lab in beautiful York to work on protein-RNA interactions in FMDV, then follow up with virology experiments at the world-leading Pirbright Institute🧬 Please share widely!

Princess paper on "Can [FeFe] hydrogenases be rationally engineered for improved performance?" is out. Thanks for involving me in this.👇👇👇