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📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly bit.ly/4b8wpNA

📢ACCESS DENIED!! Ever wonder how heterochromatin causes transcriptional gene silencing and is epigenetically inherited? Excited to share our new story showing that histone deacetylation, a conserved feature of heterochromatin domains from yeast to mammals, limits access to

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

🎉 Exciting Announcement! 🎉 “Histone Modifications and Chromatin Structure Symposium” 🗓️ Dates: October 17-18, 2024 📍 Location: National Institutes of Health, Bethesda, Maryland The NCI Center of Excellence in Chromosome Biology is delighted to invite you to our upcoming

Excited to share our latest review article “Introns with branchpoint-distant 3′ splice sites: Splicing mechanism and regulatory roles”. Check it out: sciencedirect.com/science/articl… Shravan Kumar Mishra Anupa T Anil Rakesh Pandian Dept. of Biological Sciences (DBS), IISER Mohali IISER Mohali #RNAbiology #splicing #RUBL

Our two papers on a new killer meiotic driver in 𝘚. 𝘱𝘰𝘮𝘣𝘦 have been published. It encodes a single protein that can act as both a toxin and an antidote. pnas.org/doi/10.1073/pn… pnas.org/doi/10.1073/pn…

We are happy to share our paper on the regulation of pre-mRNA splicing, “Psr1 phosphatase regulates pre-mRNA splicing through spliceosomal B complex factor Snu66,” now out in The FEBS Journal! Read it here: febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Scared to share this after 10 freaking years of waiting but here we go: We found that temperature *perception* can change the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance! biorxiv.org/content/10.110…

🔬 Decoding Silencing: How Heterochromatin Transcribes to Silence Itself! 🧬Our latest research reveals how a pioneer transcription factor-like complex PhpC/NF-Y infiltrates repressive heterochromatin, generating transcripts with hidden introns that kickstart RNAi-mediated

🚨“Ripping bacteria to shreds” 🚨 VCP/p97, a cellular AAA-ATPase, targets and then using its tweezer like action rips apart bacteria, protecting us from infections. A thread 🦠💥#MolecularMachines #HostDefense #cellularimmunity #microbiology Nature Microbiology

Our BS-MS 2014 alumnus Dr. Ashwin Kumar Jainarayanan, Cofounder, Granza Bio features in Forbes Europe Science & Healthcare (2025) 30 under 30 list! Truly remarkable. Congratulations Ashwin! forbes.com/profile/ashwin… Ashwin Jainarayanan

Super excited to share our latest work on visualising actin networks through ultrastructure expansion microscopy. A major leap towards high-resolution visualisation of the actin cytoskeleton. Grateful to Saravanan Palani and Anubhav Dhar for giving me this opportunity!

#authorinterview Dr. Rakesh K. Sahu Rakesh K. Sahu working with Dr. Shiv I.S. Grewal lab Shiv Grewal NIH talks about his work on "Protecting heterochromatin from the remodeling machines" published in Molecular cell. biopatrika.com/academia/resea… via Biopatrika

So proud of you, Sahana Holla! Watching your journey has been such a joy. Wishing you all the best as you begin this exciting new chapter at TIFRH. They’re lucky to have you!

Indeed a proud moment for IISER Mohali Dept. of Biological Sciences (DBS), IISER Mohali. Hearty congratulations to @Rhitoban Aanchal Panchal Renuka Agarwal Anjali Rana Binay Aswal and Ruchira Sen.