Two salons hosted by Manolis Kellis this weekend in Syros: John Ioannidis tomorrow on Medicine, Evidence and the Nature of Disagreement”, and myself on Saturday launching my new book with a discussion on “Truth, Infinity and Godel’s Incompleteness”. facebook.com/share/p/iU3J9e…

Thinking about AI & Drug Discovery as a postdoc? This week our CEO Rabia will be speaking as part of Schmidt Sciences' AI in Science Postdoctoral Fellowship Program schmidtsciences.org/schmidt-ai-in-…

Excited to share our latest short review, written together with Steve L. Bonilla and Jonesy, on #RNA conformational ensembles. Check it out at: sciencedirect.com/science/articl…. Particularly proud of Figure 1!

The new Serna Bio website goes live today. To celebrate the launch we're revisiting our STaR rules work one year on - thanks Tim Allen. Take a look at the site and catch up on our progress here: serna.bio

Very excited to share our latest preprint, led by rockstar post-doc Ivana Borovská. Our humble attempt to begin exploring #RNA secondary structure ensembles in a living cell (biorxiv.org/content/10.110…) (1/n)

New preprint from the lab with both Adrian Ferré-D'Amaré and @tiwarylab! In this work we study the disconnect between affinity and activity of a series of RNA small molecule ligands using structure, chemistry, and AI-augmented MD! biorxiv.org/content/10.110…

Urgent and transparent investigation needed into deadly crackdown on protest amnesty.org/en/latest/news…

The promise of a rare disease $1T moonshot 🧬💊🚀 Imagine a new version of NMN or Vitamin C optimized by AI that extends lifespan in sick kids and extends healthspan in aging adults. That’s the reason to HODL $CURES. Here’s how it could happen 👇 🔗 app.bio.xyz/launchpad/Cure…

Solana’s first BioDAO might have just uncovered the first treatment to a fatal rare disease. DeSci accelerating medicine at the speed of Solana 🧪

"Serendipity and following your heart are often undervalued, yet they can lead to the most transformative opportunities when embraced." 🌟

In Part 2 of my conversation with Rabia T. Khan, Founder & CEO of serna bio, on The Biotech Startups Podcast, we dive into how embracing serendipity and staying true to your passions can unlock groundbreaking opportunities in biotech. 💡 Rabia shares her journey and insights on

"Curiosity is essential—it's the spark that drives learning and innovation. 'Why' is my favorite word because it opens doors to understanding. Yet, as we age, it's remarkable how much of that curiosity fades away." 🔍

Congratulations to my longtime friend Mark Carney on his election victory. Leaders with a clear grasp of the global economy are precisely what this moment calls for.

A periodic reminder to leave behind simplistic & naive notions.

Still there

I am so incredibly excited to share our latest work, on the exploration of #RNA secondary structure ensembles and discovery of RNA regulatory structural switches in bacteria and human cells, out today in Nature Biotechnology: nature.com/articles/s4158…. A short tread! (1/n)

#Guanidine was known since the 1870s to affect muscle function. Vertebrates have guanidine-sensing #riboswitch RNAs linked to genes relevant to muscle disorders, including some for Ca2+ signaling and others relevant to #ataxia symptoms. Nature Communications nature.com/articles/s4146…

Optimism in the china / US biotech war nytimes.com/2025/08/17/opi…

A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: scim.ag/4lAiKmF

SpliceVarDB: A comprehensive database of experimentally validated human splicing variants. Mark Cowley & co-workers report in AJHG #ASHG25 hubs.li/Q03Nybxh0