Sarcomas with lymph node metastasis -Epithelioid sarcoma -Clear cell sarcoma -Rhabomyosarcoma -Synovial sarcoma -Angiosarcoma Dr. Allison #USCAP2023 #BreastPath #everydaybreast #surgpath #PathTwitter #PathX #pathresidents #pathology #pathologists

A constellation of hemophagocytosis #PathTwitter #PathX #hematology #hemepath #hematopathology

Case of Matrix-Producing Metaplastic Carcinoma 🔬 Historically a subtype of metaplastic carcinomas with mesenchymal elements, matrix-producing metaplastic carcinoma shows abrupt transition of epithelial cells to chondroid/osteoid matrix. #PathX #PathTwitter #breastpath

Very happy to see our paper on TRBC1 immunohistochemistry in T-cell lymphomas published in the American Journal of Surgical Pathology!

3 yo boy. Past medical history of B-ALL, KMT2A-R at age of one. S/P ASCT. Now presents with a paraspinal mass. Negative stains: CD19, CD79a, CD20, PAX5, TdT, CD3, CD34, CD117, MPO. FISH on fresh tissue shows 100% KMT2A-R. What do you think is happening here? Answer in comments 😉

Female Patient Lower abdominal wall nodule of 2 years Hx : Previous Caesarean section 3 years back and Cyclic lower abdominal pain #Gynpath #Cytopath #Pathresidents

💉🫁Transthoracic #FNA #cytology of pleuropulmonary mass(w/ a magnificent cell block! 🔬Cell clusters w/ nuclear pleomorfism and abundant pale,fragile cytoplasm. 🏷️PAX8, CD10➕. TTF1 neg Dx: RCC hematogenous spread mtt. #cytopath #pulmpath #cytohistocorrelation International Academy Cytology

I always worry about missing #AIS on #papsmear (s). Then I see one and am reminded of the ABUNDANCE of material with classic features: ☢️elongated hyperchromatic nuclei 🦅feathering 🍳saucepan handles (elongated cytoplasm) 🤪crazy pavement (disorganised) #gynpath

The Bethesda system for thyroid cytology helps classify cytopuncture (fine needle aspiration) results and guide diagnosis. Here are 10 key scenarios in category III (AUS/FLUS) that require careful interpretation for proper follow-up.

Throwback to an early 90s hit...I like big cells and I cannot lie. I'm hooked and I can't stop starin'. Oh, baby, I wanna get with ya. And take your picture... Guess what the big cells are in this marrow? Substantial clue in followup post. #hemepath

BMB 50 yo female, new pancytopenia. On flow - 10% blasts positive for CD117 and negative for CD34. Can you tell what is the IHC shown here?

Important message No2! #IACwebinar with Dr Mauro Saieg, MD, PhD, FIAC Pancreaticobilary #classification #cytology International Academy Cytology Esther Diana Rossi Ivana Kholová Lola Lozano

CC371. An increasingly common scenario: Elderly patients with cervical (and parotid) metastases from skin tumors. The big four: SqCC, melanoma, Merkel, and this one⬇️. Poirot knew the very well Cervical node in an old patient with a scalp tumor Kalyani Bambal Barry McGinn #cytopath

#hemepath PB and marrow smears. ALK+ALCL, leukemic!!

#hemepath Langerhans cell histiocytosis

Bone marrow biopsy, a 87 yo male, previous diagnosis of CMML. Shown here: H&E, CD123, CD56, CD4. Also positive for TCL1 and IRF8. No skin involvement.

Bone marrow involvement by Hodgkin lymphoma (stain is MUM) #pathology #PathTwitter #pathX #hemepath #pathresidents

CC372. ORGAN and DIAGNOSIS. The importance of clinical information is directly proportional to the value that morphology has without it. Their combination is extremely synergistic, but it is advisable to know how to handle them separately #cytopath