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Untouchability across India (from paper by Amit Thorat & Omkar Joshi). It’s virtually gone in some states &, sadly, very prevalent in some others. One hopes the latter will learn from the former.

Zones & Patterns of Liver Injury Zone 1 (ALT > AST) ▪️Autoimmune hepatitis ▪️Viral hepatitis Zone 3 (AST > ALT + ⬆️ LDH) ▪️Ischemia ▪️Toxic events ▪️Heart failure ▪️Budd-Chiari syndrome Note: ALP is predominant in basolateral membrane #LiverTwitter 👊

Fun fact: we contain ~0.6 kg macrophages and ~1.2 kg immune cells in total Interesting paper: pnas.org/doi/full/10.10… *calculations based on "a standard reference human, historically characterized as a male between 20 and 30 y old, weighing 73 kg, and having a height of 176 cm"

And those who were seen dancing were thought to be insane by those who could not hear the music.

We live in a highly patriarchal society. I hv done around 200 kidney transplants. My findings in my series: 1. Around 80-90 % of Kidney Transplant Recipients are men. When a woman develops ESRD( Kidney Failure), it is very hard to find a Kidney donor, among the relatives. 2. In

Ultimately, it is the desire, not the desired, that we love.

(1/2) ICMR’s research study exploring the causes of the anecdotal reports of sudden deaths in healthy young adults is now published. Here are the key findings (read in thread). Link to the study:journals.lww.com/ijmr/abstract/…

Congratulations to Arindam Talukdar and Partha Chakrabarti labs! J Med Chem ACS Publications: a small molecule curbs ATGL ubiquitination by the E3 ubi ligase COP1, enhances hepatic lipolysis and reverses hepatic steatosis. CSIR, India Vibha Tandon DSTIndia Department of Biotechnology pubs.acs.org/doi/10.1021/ac…

A politician divides mankind into two classes: tools and enemies.

To live is to suffer, to survive is to find some meaning in the suffering.

Beware that, when fighting monsters, you yourself do not become a monster... for when you gaze long into the abyss. The abyss gazes also into you.

when they decide to descend to the modesty of hypotheses, a provisional experimental point of view, a regulative fiction- though always within the restriction that they remain under police supervision, under the police of mistrust... Friedrich Nietzsche on Science

📢Check out our latest article in ACS Med Chem Lett on anti-cancer activity of Biselyngbyolide B analogues by Debobrata Paul @Himangs89552410 Sanu Saha, and PRATITI MANDAL of CSIR-IICB. Thankful to Partha Chakrabarti for this collaborative project. ➡️doi.org/10.1021/acsmed…

Adipose tissue–derived adipsin marks human aging in non-type 2 diabetes population drc.bmj.com/content/12/4/e…

Happy Teachers day to all. #TeachersDay #SavitriBaiPhule

Pathophysiological hallmarks in type 2 diabetes heterogeneity (review) pubmed.ncbi.nlm.nih.gov/40166449/

Rational design and discovery of potent PROTAC degraders of ASK1: A targeted therapy in MASH - now published in RSC Medicinal Chemistry pubs.rsc.org/en/content/art…