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Does scattering limit your in vivo imaging experiments? We 'super-resolve' neurons using the same trick how PALM/STORM microscopy resolves individual molecules (1/12).

The #cellsurface is a hub of complex interactions where proteins, small molecules, and cells communicate. Join experts HHMI | Janelia to explore the latest research shaping our understanding of this critical interface! #cellbiology Apply by May 20 @ janelia.news/SRF25

We used cryoEM and mass spectrometry glycoproteomics plus GlycoSHIELD to determine the molecular structure of human coronavirus 229E spike protein in complex with its human receptor, hAPN in a 6:2 binding stoichiometry. doi.org/10.1038/s41467…

Vittani, Lee, Wang, Hiraoka, et al. KI mouse expressing red fluorescent blood In situ SpyTag/Catcher attachment of biosensor ECS SpyCatcher to capture BBB leak doi.org/10.1101/2025.0… We hope this method is useful to a wide range of the biology community.

2025 IBC summer #intern program applications are now open! 👉Application deadline: 2025/4/30 👉For more information, please visit: ibc.sinica.edu.tw/SummerInternsh…

Join us at the Quantitaive Microbiology Symposium next Mon and Tue at Academia Sinica in Taipei! sites.google.com/view/qmicrob20…

We are delighted to invite you to a seminar presented by Dr. Michael Z. Lin from Stanford University. Join us this Thursday IBC Academia Sinica for this opportunity to learn about groundbreaking techniques for visualizing neuronal activity. We look forward to seeing you there!

We are seeking candidates for a fully funded postdoctoral position (3 years) in the Shaner Lab at UCSD. The successful candidate will lead projects focused on genetically encoded biosensor design, validation, and optimization. adc-nice.org/postdoctoral-r…

Improved genetically-encoded GABA indicators are now published. iGABASnFR2 has 4.2X better sensitivity and 20% faster kinetics; detects direction selective GABA release in retina 📰Preprint: bit.ly/4hISy7b 🧪Plasmids & AAVs: bit.ly/3FDh8Jl Addgene HHMI | Janelia

Congratulations to graduate student Ayse Sahan and former student Shawn Mingyuan Chen on the publication of their lipid biosensors in PNAS! pnas.org/doi/full/10.10…

生体の科学という雑誌で、ゲストエディターとして、「AIにより加速する生体分子デザイン」という特集を企画し、多くの先生方からご寄稿いただきました。生体分子デザインに関する最新の知見を日本語で読むことができますので、ぜひご覧ください! igaku-shoin.co.jp/journal/detail…

Excited to share our new paper out in nature revealing cell-type specific nuclear organization and its link to gene regulation using new spatial multi-omics technologies! nature.com/articles/s4158…

Far-red fluorescent genetically encoded calcium ion indicators: nature.com/articles/s4146… New two far-red fluorescent GECIs (calcium indicators): - FR-GECO1a: λex max=596 nm, ΔF/F0=6, Kd=29 nM - FR-GECO1c: λex max=644 nm, ΔF/F0=18, Kd=83 nM

【お知らせ】令和7年度より、「海外特別研究員」の滞在費・研究活動費の支給額を年額約520万円～800万円（派遣都市・国によって異なる）に増額しました。新単価及び新区分は令和7年4月1日以降の採用期間に適用されます。詳細は、下記ウェブページをご確認ください。 jsps.go.jp/j-ab/keiji/202… #JSPS

2025 #summer #intern program applications are still open! Feel free to contact our PIs if you have any questions. 👉Application deadline: 2025/4/30 👉For more information, please visit: ibc.sinica.edu.tw/SummerInternsh…

Join the "Genetically-Encoded and Chemigenetic Tools for Analysis and Control of Biological Systems" symposium at #ChemPacific2025! Explore cutting-edge tools alongside other world-class science in Hawaii. 🏝️ Pacifichem.org

Check out our new paper in Nature Biotechnology sharing our latest kinase activity reporters! Led by former postdoc Michelle Frei, these reporters are based on HaloTag rather than an FP, for far-red imaging and superresolution! nature.com/articles/s4158…

Excited to share that our preprint is out in Nature Methods! 🎉 In revision, we show how ALI outperforms NMF, VolPy & Cellpose in crowded neuron detection, and works well with light-sheet & targeted illumination microscopy. Read the final version here 👇 nature.com/articles/s4159…

7月23日（水）開催　2024台日神経科学研究者交流会 jnss.org/academic-event…

【新刊】 実験医学増刊号「脳と体をつなぐ要　グリア細胞と疾患」が本日6/5（木）に発行となりました。 グリア細胞研究の全てがわかる決定版！睡眠や学習・記憶といった行動レベルへの関わりから、アルツハイマー病やパーキンソン病への関与まで、神経回路の「縁の下の力持ち」の雄弁な素顔に迫る！