Good news! @mastprogram shows that while the duodenal #microbiome of those who smoke changes, ex-smokers have a microbial pattern more similar to those who never smoked! Our data is published in Scientific Reports-rdcu.be/cLkw8 BTW-better just not to smoke, like ever(my PSA!)

Small but mighty! This is a video of a killer T cell of the immune system destroying a monstrous ovarian cancer cell. I recently captured this data on a spinning disc confocal microscope.

Super important from #REIMAGINE study to assess small bowel microbiome. You must use a protected catheter. You must get both free fluid and mucus (viscous). You must break the mucus before sequencing. Years of work to get this validated.

Love this poster at #DDW2023 and Digestive Disease Week. “Physician Scientists or Celebrities? Kardashian Index of Gastroenterologists” Lead author: Ugonabo Onyinye Love to see Mayo Clinic Gastroenterology & Hepatology leading the way! Perhaps the “or” should be an “and/or”? 🤷🏻‍♀️ I know plenty who are both! 🌟

Excited to see this new tech from #DDW2023 via Jan Král - a capsule that can be swallowed at home to take endoscopic images of the GI tract. What do people think of it?

Big take away from #DDW2023. The gut is connected to everything a human is, does, and goes through. What people do and go through changes the gut, the immune system, and the microbiome. We need to work from every angle to give a person’s gut the best care! #wholepersoncare

Today Juliana from our MAST Research Program from Cedars-Sinai Academic Medicine presents the impact of CdtB toxin. This toxin from food poisoning leads to #SIBO in animals that is almost exactly what we see in humans. Hydrogen producers go up. Hydrogen sulfide producers go up. And the host markers link

Fascinating new preprint on bioRxiv tackles a whale of a question: Whales are huge. So why don’t they get a ton of cancers? biorxiv.org/content/10.110…

Out now in nature: Profiling the human intestinal environment under physiological conditions By Dari Shalon, Rebecca Neal Culver, Jessica Grembi, Jacob Folz, David Relman, Kerwyn Casey Huang & colleagues. @DavidRelman nature.com/articles/s4158…

This is a great article featuring Ruchi Mathur MD from MAST Research Program Cedars-Sinai Academic Medicine highlighting her and the teams (Gabriela Leite, PhD et al) expertise on aging and the #microbiome. So much more to come on #microbiome from MAST very soon. inverse.com/health/centena…

We’re excited to announce our new manuscript published in the most recent issue of Cell, in which we explore insights generated from ultra deep-sequencing of the gut microbiome of Hadza hunter-gatherers of Tanzania. cell.com/cell/fulltext/…

Today we report a detailed map of interactions between the immune system and the gut microbiome. Kazuki Nagashima led the charge w/ help from Aishan Zhao and Kat Atabakhsh. nature 1/40 nature.com/articles/s4158…

The disturbances in the gut–brain axis are associated with different types of pain Some probiotics, FODMAP diet and fecal microbiota transplantation can help in treating visceral pain: ow.ly/86q450Py29K

New RTE Brainstorm piece led by Teagasc and VistaMilk Research Ireland Centre colleague, Kanishka Nilaweera: “Here's how whey proteins can reduce fat stored in the body”rte.ie/brainstorm/202… via RTÉ

In 1992 scientist thought that 4% of all species on belonged to bacteria and 73% to animals. But in 2017 thanks to all the DNA sequencing data scientists discovered that 78% of all the species on our planet belong to Bacteria and only 7% to animals? wienslab.com/Publications_f…

What do #FoodAdditives do to our gut? Mostly pre-clinical (in vitro, animals) Aaron Bancil drew this great summary👇🏽 Plus tables and review of studies of ➡️Emulsifiers ➡️Sweeteners ➡️Food colours ➡️Nanoparticles Free to read rdcu.be/dzlO1 #ECCO24 #ECCO2024

"Fermented foods, their microbiome and its potential in boosting human health"- a new review with inputs from Teagasc's Paul Cotter and Prof. Orla O’Sullivan. Read the full paper (open access) here in Microbial Biotechnology: ami-journals.onlinelibrary.wiley.com/doi/pdf/10.111…

In 2016, I reported concerns about papers published in Springer Nature's Oncogene Journal. I sent a reminder in 2019. I sent another reminder two weeks ago. Their senior publishing editor just wrote me back saying that the investigation is still ongoing. 😭😭😭😭😭

Very excited to finally have my PROMOTe trial paper out in Nature Communications! We showed that a prebiotic food supplement can improve cognition versus placebo. The gut microbiome holds huge promise as a therapeutic target for age-associated morbidity. nature.com/articles/s4146…

📕#RedJournal: Characterization of the Small Bowel Microbiome Reveals Different Profiles in Human Subjects Who Are Overweight or Have Obesity Leite, et al. 👉 bit.ly/3KKCBzs Gabriela Leite, PhD Gillian Barlow, PhD Daniel Cohrs, MD Ali Rezaie MD MSc Mark Pimentel MD Ruchi Mathur MD