PALB2 and BRCA1 tumor suppressors interact via their coiled-coil domains to resolve DNA damage. Our recent structure of the PALB2 coiled-coil domain helps in assessing how missense mutations affect the PALB2/BRCA complex's function. doi.org/10.1042/BSR202…

Happy to announce availability of our reviewed preprtint getting online in eLife - the journal: The mechanism of DRB7.2:DRB4 mediated sequestering of endogenous inverted-repeat dsRNA precursors in plants doi.org/10.7554/eLife.…

Please RT. Thanks

Unveiling the world's first-of-a-kind 1.3 GHz high-res #NMR system! The 1.3 GHz NMR spectrometer by #Bruker features a groundbreaking hybrid LTS-HTS superconducting magnet. Read more: goto.bruker.com/3XUQguS Discover more about the 1.3 GHz NMR system: goto.bruker.com/4j5PHXF

Colon Cancer is no longer an "old person's disease.” It's now one of the leading causes of death in people under 40. But it doesn't have to be. Here's what's causing it, how to protect yourself (& how to cleanse your colon):

Accepting the first #NASaward of the ceremony, the 2025 Alexander Hollaender Award in Biophysics, is #NASmember Lewis E. Kay of University of Toronto, honored for seminal contributions to understanding protein folding, dynamics, and function. #NAS162 #biophysics Watch: ow.ly/yRNR50VIrX7

Artificial Intelligence is revolutionizing healthcare, from detecting TB, cancer, and strokes to enhancing minimally invasive surgeries. Glad to share my insights for this detailed article . deccanchronicle.com/tabloid/hydera… #AIinHealthcare #AIinSurgery #RoboticsinMIS #AIGHospitals

Dr. Mandar V. Deshmukh & his team show how proteins are not static molecules. Their structures are flexible, and this allows them to bind to a lot more number of substrates than otherwise possible. They have found this to be true for dsRNA binding proteins in plants. pubs.acs.org/doi/10.1021/ja…

Rare but Real: Portal Annular Pancreas (PAP) poses unique surgical challenges during Whipples - AIG Hospitals' Department of Surgical Gastroenterology Click doi.org/10.14701/ahbps… to read the full article. #WhippleProcedure #AIGHospitals #GISurgery #Pancreatoduodenectomy

"We fail much more than we ever succeed. We know that. We accept that. We're amazing at dealing with failure. That's what scientists do." 2021 chemistry laureate David MacMillan on what failure means to him. What does failure mean to you?

Introducing in-cyclo NMR, a new method led by Guillaume Mas at Biozentrum, University of Basel (Nature Communications)! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s41467…

#ResearchExplained! In a first, Vivek Hari Sundar & team from Dr Shiva prasad's group at NCBS has identified a new H4 histone variant in rice which may have helped semi-aquatic rice varieties adapt to changing environments.🌾 Read here:bit.ly/4jNcirp By Rupsy Khurana

If you have ever wondered why many DNA/RNA-binding proteins have negatively charged IDRs, this review may be helpful. pubs.acs.org/doi/10.1021/ac…

on behalf of Pro James Keeler (University of Cambridge) considering the possibility of revising the text and creating a third edition : Understanding NMR Spectroscopy, James Keeler - survey concerning a possible third edition cambridge.eu.qualtrics.com/jfe/form/SV_77… #NMRbooks #NMRchat #NMR 🧲

There's been amazing progress against liver cancer over the last 60 years (Specifically, hepatocellular carcinoma treated with surgery) What's driven the progress? Earlier detection, safer and better operations, better biomarkers, and better treatment of recurrence

100 years have gone by, and we still donot know what it really means.

The complexities and entire gamut of functions of proteins cannot be captured in their static images. Studies from Dr. Sankaranarayanan Rajan and Dr. Mandar V. Deshmukh highlight the importance of detailed understanding of protein composition and dynamics.

Publication alert! Krishnan, I & Sanjay DNA to RNA Tuning of a Pyrrolidine-Derived Quinoxaline Scaffold: Magnesium Induces Binding and Inhibition of Internal Ribosomal Entry Site RNA-Mediated Translational of HCV | ACS Pharmacology & Translational Science pubs.acs.org/doi/full/10.10…

GV Rx : A10 kg dumbbell might look miniscule and featherly to lift, but 10 kg on your body is humongous to carry . Choice is yours. #TransformationGoals #HealthMatters #WeightLossJourney #BodyTransformation #HealthGoals #SmallStepsBigImpact #FitnessMotivation #BodyGoals