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Russen-Bots des #Doppelgänger-Netzwerks sind aktuell aktiv in mir noch nicht begegneter krasser Schlagzahl und Bandbreite.

Now published: DIY microscope🔬 for insects of all sizes, even those preserved in ethanol! Designed for developing holistic biomonitoring with AI tools. Most animal species and much of animal biomass are arthropods. They need frugal identification methods! ieeexplore.ieee.org/document/10401…

Promise: Q40. Reality: See below. .@TGen hits >Q50 on most bases with real liquid biopsy samples on #Onso. #AGBT #AGBT24 #PacBio

BRAKER3: Fully Automated Genome Annotation Using RNA-Seq and Protein Evidence with GeneMark-ETP, AUGUSTUS and TSEBRA doi.org/10.1101/2023.0…

Miniprot v0.13 released with support of non-standard translation tables, minor improvement to junction accuracy and a couple of bug fixes. github.com/lh3/miniprot/r…

Every one who depends on purified plasmid for anything they do needs to read and think about that paper. ... and every cloner needs to functionally work that in to how they screen and QC their plasmids before the next step

Our single cell atlas on the annelid Pristina leidyi finally out in Nature Communications! A great pleasure to work and learn from this wonderful team! Jordi Solana B. Duygu Özpolat, Ph.D. Helena García Castro Elena Emili Irene del Olmo Nathan Kenny apposada David A. Salamanca-Díaz AlexaBely

At Oxford Nanopore we have successfully sequenced a yeast chromosome, telomere to telomere, in one read.

Look to the sky for the BATT signal (or click the link below to read about it): A niche-derived nonribosomal peptide triggers planarian sexual development | PNAS pnas.org/doi/10.1073/pn…

Gene Myers just released super fast whole genome aligner github.com/thegenemyers/F…. He and Chenxi Zhou and I have lots of ideas for downstream use.

Planarians are model systems for stem cells & regeneration. Ivanković et al. provide new genome assemblies of S. mediterranea & 3 relatives, showing that synteny is not an evolutionary constraint in flatworm genome evolution. Jeremias Brand MPI for Multidisciplinary Sciences Rink Lab nature.com/articles/s4146…

The new PacBio SPRQ chemistry for the Revio system has some big advantages for micro and #metagenomics: - Input requirement drops from 2 micrograms to 500 nanograms (per SMRT cell) - 30% increase yield per cell (~90Gb -> 120Gb) pacb.com/press_releases…

Today, we announced the first #PacBio benchtop long-read sequencing system, Vega. #Vega delivers all the functionality of #Revio into a compact, lower- throughput benchtop platform. bit.ly/3O0mP5b #ASHG24 #ASHG2024

Rosemary Sinclair Dokos presenting an update on the Oxford Nanopore technology #ASHG2024

In #NextGenSequencing news, Oxford Oxford Nanopore presented at #ASHG24, including the new flow cell chemistry that gives more robust yields for a wider range of insert sizes. The R&D version increases yield by 33% (150Gb) over the released version for a 30kb human DNA sample.

I am thrilled to share our paper nature.com/articles/s4146… Mitochondrial dynamics govern whole-body regeneration through stem cell pluripotency and mitonuclear balance| Nature Communications great collaboration Liangyi Chen Zhixing Chen

DIAMOND v2.1.11 is now available, providing numerous improvements and fixes. github.com/bbuchfink/diam…

1/? 🧬 New Breakthrough in Duchenne Muscular Dystrophy (DMD)! Our new paper in nature reveals how utrophin—a dystrophin “backup”—is upregulated in DMD. The key? Transcriptional adaptation (TA), triggered by mutant mRNA decay, not protein loss. 🔗 doi.org/10.1038/s41586…

Deep-learning-based single-domain and multidomain protein structure prediction with D-I-TASSER nature.com/articles/s4158…

Huge thanks to @ACHSEeV, the Köhler Foundation, and our brilliant team Stainier Lab @MPI_HLR. Science is a team effort, and this award recognizes that shared dedication. More here 👉 mpi-hlr.de/391963/news_pu… #RareDisease #EvaLuiseKöhler #Duchenne #DMD #TranscriptionalAdaptation