Shi Yan (@mryanshi) 's Twitter Profile
Shi Yan

@mryanshi

biochemist, glycobiologist, biotech enthusiast, interested in infectious diseases and cancer #glycotime

ID: 4696739575

linkhttp://orcid.org/0000-0003-4949-9140 calendar_today02-01-2016 14:46:57

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Nathan Lewis (@nathan_e_lewis) 's Twitter Profile Photo

Excitng collaboration in which we expressed a hepatitis c vaccine candidate in a panel of glycoengineered CHO cell lines. This allowed us to find a specific glycan structure that greatly improved immunogenecity, even for more distant strains #glycotime nature.com/articles/s4154…

Robert P. de Vries (@robertpdevries1) 's Twitter Profile Photo

New paper of Yunfei! Here, he synthesized sulfonates in different sialylated epitopes... although not better ligands for most lectins tested, they were tolerated and even preferred by siglec-4. #glycotime pubs.acs.org/doi/10.1021/ja…

Gavi, the Vaccine Alliance (@gavi) 's Twitter Profile Photo

The first ever chikungunya vaccine is starting to be rolled out. Could it help bring an end to this mosquito-borne disease? bit.ly/4jSO9jb

GlycoUniverse (@glycouniverse) 's Twitter Profile Photo

🚨 Glyconeer® Workshop 2025 📍 Potsdam | 📅 July 2–4 We’re bringing together global #Glyconeer users, Max Planck Institute of Colloids and Interfaces scientists & glycan enthusiasts for 3 days of insights, updates & exchange! Join the conversation on the future of automated glycan assembly! 💬✨ #glycotime

🚨 Glyconeer® Workshop 2025
📍 Potsdam  | 📅 July 2–4

We’re bringing together global #Glyconeer users, <a href="/MpiciPotsdam/">Max Planck Institute of Colloids and Interfaces</a> scientists &amp; glycan enthusiasts for 3 days of insights, updates &amp; exchange!

Join the conversation on the future of automated glycan assembly! 💬✨ #glycotime
Robert P. de Vries (@robertpdevries1) 's Twitter Profile Photo

And now published! #glycotime "Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68" fantastic collaboration with Lisa Bauer Debby van Riel The Boons Group enjoy 👍pubs.acs.org/doi/10.1021/ac…

Xander de Haan (@haanxander) 's Twitter Profile Photo

New review paper from the influenza group Utrecht Virology Lab together with Mengying Liu and Erik de Vries on virion motility of sialoglycan-cleaving respiratory viruses through mucus and on cells in NPJ viruses Nature Portfolio doi.org/10.1038/s44298…

New review paper from the influenza group
<a href="/UtrechtVirology/">Utrecht Virology Lab</a>
together with Mengying Liu and Erik de Vries on virion motility of sialoglycan-cleaving respiratory viruses through mucus and on cells in NPJ viruses <a href="/NaturePortfolio/">Nature Portfolio</a> 
doi.org/10.1038/s44298…
Wai-Hong Tham (@tham_lab) 's Twitter Profile Photo

Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕 🦟 Transgenic parasites without Pfs230 D13D14 do not transmit 🦙 💉Nanobodies + mRNA induced antibodies reduce transmission New in Science Magazine science.org/doi/10.1126/sc… #ScienceResearch #Malaria

Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕

🦟 Transgenic parasites without Pfs230 D13D14 do not transmit

🦙 💉Nanobodies + mRNA induced antibodies reduce transmission

New in <a href="/ScienceMagazine/">Science Magazine</a> 

science.org/doi/10.1126/sc…

#ScienceResearch #Malaria
Alba Silipo (@albasilipo) 's Twitter Profile Photo

👇Structure of the Lipopolysaccharide from Paenalcaligenes hominis: A Chemical Perspective on Immune Recognition | JACS Au #Paenalcaligenes #glycotime #aging #Microbiota #Aging #GutBrainAxis #bacteria #immunity Ferran Nieto FlavianaDiLorenzo Tony pubs.acs.org/doi/10.1021/ja…

Shi Yan (@mryanshi) 's Twitter Profile Photo

Many thanks for sharing our new #glycotime paper! A great team effort built on years of research on worm glycosylation, initiated in the Wilson lab Iain Wilson 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇦🇹. Proud to contribute by exploring its application in novel vaccine development. 💉🐏🐑🪱

Vijay Rathinam (@rathinamva) 's Twitter Profile Photo

Why does RNA undergo glycosylation? Excited to have our new paper out. We in collab w/ Ryan Flynn show N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells. nature.com/articles/s4158… UConn Health UConn Research

Why does RNA undergo glycosylation? Excited to have our new paper out. We in collab w/ Ryan Flynn show N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells. nature.com/articles/s4158… <a href="/uconnhealth/">UConn Health</a> <a href="/UConnResearch/">UConn Research</a>
Ryan Weiss (@rjweiss86) 's Twitter Profile Photo

I'm excited to share our paper detailing a new sensitive and accessible LC-MS method for analysis of GAGs and non-reducing end biomarkers for lysosomal storage disorders! This was a great collaboration with the Azadi and Boons groups Parastoo Azadi! #glycotime pubs.acs.org/doi/10.1021/ac…

Shinya Fushinobu (@sugargroove) 's Twitter Profile Photo

涙の糖プロテオームの詳細な解析により、ラクリチンの多様な糖鎖付加とスプライソフォームが明らかに #glycotime In-depth analysis of the tear fluid glycoproteome reveals diverse lacritin glycosylation and spliceoforms - Journal of Biological Chemistry jbc.org/article/S0021-…

Shi Yan (@mryanshi) 's Twitter Profile Photo

After traveling 10000 km around the globe, I am very happy to join the opening ceremony of the #WAAVP congress with so many participants and colleagues, in the beautiful city #Curitiba in Brazil 🇧🇷 Many things about #parasite are be learned!

After traveling 10000 km around the globe, I am very happy to join the opening ceremony of the #WAAVP congress with so many participants and colleagues, in the beautiful city #Curitiba in Brazil 🇧🇷 Many things about #parasite are be learned!
Marcin Czerwinski (@czerwinsmarcin) 's Twitter Profile Photo

New from our lab: Krzysiek Mikołajczyk Katarzyna Szymczak et al. show which expression system is better for glycosylated proteins: Trichoplusia ni insect cells (High Five) or human embryonic cells (Expi293F). Location of the 6xHis-tag also evaluated. tinyurl.com/2xkmxtet #glycotime

New from our lab: <a href="/k_mikolajczyk/">Krzysiek Mikołajczyk</a> <a href="/katszymczak/">Katarzyna Szymczak</a> et al. show which expression system is better for glycosylated proteins: Trichoplusia ni insect cells (High Five) or human embryonic cells (Expi293F). Location of the 6xHis-tag also evaluated. 
tinyurl.com/2xkmxtet
#glycotime
Belen Sotomayor (@belensotomayor5) 's Twitter Profile Photo

My PhD work is out in Nature Communications !✨For the first time, we show that bacteria can glycosylate full-length monoclonal antibodies. A proof of concept and a key step toward making antibody therapies accessible to all.. nature.com/articles/s4146… #biotech #glycotime #SyntheticBiology

My PhD work is out in <a href="/NatureComms/">Nature Communications</a> !✨For the first time, we show that bacteria can glycosylate full-length monoclonal antibodies. A proof of concept and a key step toward making antibody therapies accessible to all..  nature.com/articles/s4146… #biotech #glycotime #SyntheticBiology
Shi Yan (@mryanshi) 's Twitter Profile Photo

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease | Nature #glycotime #ageing nature.com/articles/s4158…

Florian Krammer (@florian_krammer) 's Twitter Profile Photo

Did you know amphibians and fish have viruses that are very similar to human influenza B viruses? We didn't know either, but Eddie Holmes found them and we had a closer look at their HAs and NAs. with Gagandeep Singh| ਗਗਨਦੀਪ ਸਿੰਘ The Ward Lab Robert P. de Vries Disha Bhavsar science.org/doi/10.1126/sc…