Heart contractility doesn’t just pump blood; it shapes development. This study shows that the physical force of a beating heart switches on a key gene (id2b) that helps build heart valves and supports healthy heart function. elifesciences.org/articles/10115…

Aging and optimal health is a moving target, which is why blood (and other) testing 1x/year isn't enough Then, the question is how many tests per year, until the day when we can have data every day

Longevity World Cup: The Race to Stay YOUNGER Than Your Age 🧬🏆

There's more to this story-a high protein intake, beyond what is physiologically needed, will increase blood urea levels, which is toxic to the gut barrier Moreover, high levels of urea can induce cell senescence, which highlights getting the protein intake dose right (and not

See if you can beat the current #1, Michael Lustgarten!

Updated Biomarker Optimal Ranges: HDL, Hemoglobin patreon.com/posts/updated-…

Cardiovascular autonomic dysfunction precedes cardiovascular disease and all‐cause mortality …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

On Alzheimer's disease today: —Where p-tau217 is found in the brain and what it means —p-tau 217 is the most sensitive and specific AD biomarker, systematic review —Amyloid-β in brain and the gut's immune system

"Inulin diet modulates the gut microbiome and gut immune cells and attenuates frailty in AD" cell.com/cell-reports/f… I pitched that hypothesis in 2016, now there is more proof... amazon.com/dp/B01G48A88A

The Longevity World Cup just crossed into triple digits with 101 athletes🚀

These biomarkers should be on everyone radar "An index based on CRP, RHR, HDL-C, WtHR and HbA1c was found to predict an independent outcome – mortality – as well or better than more elaborate sets of biomarkers." sciencedirect.com/science/articl…

"RHR is independently associated with longevity even when familial factors are controlled for in a twin design." Heritability of resting heart rate and association with mortality in middle-aged and elderly twins heart.bmj.com/content/104/1/…

Cloudy/Sunny! Still plenty of infrared.

Remnant cholesterol is associated with unstable carotid plaque in a neurologically healthy population svn.bmj.com/content/10/1/55

Current dietary guidelines aren’t for everybody Sarah Berry acknowledges personalized nutrition advice is needed to improve the efficacy of population recommendations ESNM.eu #NeuroGASTRO2025

Testing biomarkers many times per year and tracking diet (but also supplements, exercise, sleep, and more!) will help one more quickly realize their personalized recipe for optimal health (and potentially, longevity)

New Science Magazine A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model. science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

Michael Lustgarten's KEY To Biohacking

Higher levels of carotenoids are also associated with a younger biological age: youtube.com/watch?v=Hvk1wv…

Even in the shaded area outside, there’s an abundance of infrared light. It’s not inside. It’s only outside.