My next short is $AVXL. One drug: blarcamesine. Time is running out for Cindarella: CHMP may issue its negative opinion tomorrow, but almost definitely by the Dec meeting. Shares will drop to <$1.25, as the final nails in the coffin for this ill-conceived project are hammered.

On Monday I posted an unusual 86K call buyer on $CDTX; they paid $276 per contract. Thursday evening, $MRK announced a $9.2B buyout of $CDTX at $221.50/share. This morning these contracts opened at $8,716 each, and they sold their position for roughly $3M. In just 5 days, this

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The best book on Mining Economics and Valuation out there. Yes, there are more technical books out there. But you can’t beat this book’s value-per-page.

🧵$CAPR longer thread, full report available now on substack, link in bio. in this thread I'll get into more of the details of why CAP-1002 is about to fail its ph3 topline

A robot for the 3D printing farm! 🖨️ 3D printing is often tied to a repetitive cycle: wait for the print to finish, remove it, clean up, start the next one—and repeat. But what if there were a solution that changed all of that? This robot powers an entire 3D printer farm!

Les grands types de problèmes en Machine Learning en entreprise… et quand utiliser de l’IA Gen ( ou pas ..) ⬇️ J’ai voulu m’amuser à refaire un tour des grandes familles de problèmes en Machine Learning et à les classer entre ce qui relève du ML traditionnel et ce qui peut,

how to close enterprise clients before they realize you're 22: - answer their email in 4 minutes (they're used to 4 days) - send loom explaining the solution before they finish writing requirements doc - schedule call for tomorrow (they wanted "sometime next quarter") - on call:

What no one tells you is that you can get a 10/10 quality suit (Canali, Loro, Zegna) with a bit of maneuvering and effort for 20-30% of the original price

everyone asking how i generate 40-50 qualified sales calls per month organically fine i'll break it down but this only works if you have actual skills and real results here's the system: 1) LEAD MAGNETS THAT DON'T SUCK - notion docs with 2,000+ hours invested - actual

A random account, who has previously won $100K+ on a Gemini market, just won over $1M on every single Google Search market Senior dev doubling his salary? You cant make it up lol Account: polymarket.com/0xee50a31c3f5a…

most people think scaling means more clients WRONG i went from 20 clients at $40K/month to 8 clients at $80K/M same revenue, 75% less chaos here's what actually scales: → higher pricing (infrastructure not automation) → retainers not projects (recurring > one-time) →

how to sell $20K systems that are actually $2K systems: step 1: don't say "automation" (sounds cheap) step 2: say "infrastructure" (sounds expensive) step 1: don't say "workflow" (sounds tactical) step 2: say "intelligence engine" (sounds strategic) step 1: don't say

I think Martin has to take more accountability for his followers joining him on shorts like this. Especially shorts on binary biotech events like $CAPR. Lots of his young following don’t understand the risks of shorting. I always emphasis this, along with keeping any position

Writing 500-page thread/Analysis about bear thesis in $CAPR and $PRAX just get bent later! Okay sorry that was last one! Short sellers are Evil lads! 😜

My Tech Stack for my 2.1M users SaaS: Built solo. No team 🫡 💻 Frontend: - Next.js - TailwindCSS - Shadcn UI - Zustand 🛠️ Backend: - Fastify 🗄️ Database: - PostgreSQL (self hosted) 🔑 Authentication: - Better Auth 🏭 Infrastructure: - Digital Ocean (hosting the frontend,

Instead of adding more features, do this: 1. Launch everywhere (Hacker News, Product Hunt, Reddit, X, LinkedIn, YouTube etc.). Spend a week giving your MVP its best shot. 2. (if #1 didn't take off) — Rebrand. New name, new logo, new design, new landing page, new headline. Same

If you have applied Y Combinator you should also consider these equity-free grants too 1. Google for Startups : $100k in credits 2. Vercel : $3,600 in credits 3. @aforevc Grants $1,000 4. @joinedgecity grants : $5k-40K 5. Emergent Ventures : upto 100k 6. Thiel Fellowship : upto

YC taught us to never take a sales meeting without asking these 7 questions first: 1) What made you decide to take this call 2) Tell me about the problem. How long have you had it 3) How bad is it? Who else does it affect? 4) How do you quantify the cost/impact of this problem

This doesn't work because a "product launch" isn't what it was 10 years ago anymore Back then you'd launch on Product Hunt and you'd get thousands or tens of thousands of users overnight and journalists would pick it up after A lot has changed since then Firstly, nobody cares