How ribosomes shape protein folding go.nature.com/3TY35ST

Collaborative work of slavica pavlovic djuranovic, Yaser Hashem, Jovanovic Lab and Sergej Djuranovic - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact

Paenilamicins bind to a unique site on the ribosome to inhibit protein synthesis | Nature Chemical Biology…rdcu.be/dXZB0 nature.com/articles/s4158…

Evolutionary divergence of drug-binding sites in bacterial ribosomes biorxiv.org/cgi/content/sh… #biorxiv_micrbio

This new preprint from the Cate lab provides insights into the fate of ribosomes in stationary archaea. Using an organism adapted to 95°C, they identify a protein called Dri, which appears to act as an archaea-specific ribosome hibernation factor: biorxiv.org/content/10.110…

A manuscript describing RiboSeq.Org is out in 2025 NAR db issue: doi.org/10.1093/nar/gk… It introduced RiboSeq Data Portal: rdp.ucc.ie

Nice short/introductory review in all things ribosomes by pioneer Harry Noller in the special 50 years issue of Cell. The ribosome comes to life: Cell cell.com/cell/fulltext/…

Actinobacteria appear to possess a species-specific ribosome hibernation factor, found in Mycobacteria, that binds to the nascent tunnel of dormant ribosomes. More in this exciting study by Ojha and Agrawal lab: biorxiv.org/content/10.110…

We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: science.org/doi/10.1126/sc… The work was supported by IGBMC, Inserm, CNRS 🌍, -, @ERC_research, IMCBio Graduate School, and Instruct-ERIC. 1/7

How to regulate translation of proline containg proteins by the metabolic state of the cell? Finally out in Nat. Commun. Great collaboration with SchlundtLabNMR Pavel Kielkowski Fei Qi and Dimitrij Frishmans group: nature.com/articles/s4146…

Online Now: Structural dynamics of human ribosomes in situ reconstructed by exhaustive high-resolution template matching dlvr.it/TGXlng

V sobotu 30. listopadu 2024 se na ÚOCHB uskutečnil Grant Writing Workshop pod vedením Dr. Carlose V. Mela z Univerzity Karlovy. Účastníci se věnovali psaní abstraktů, stanovování výzkumných cílů a tvorbě narativního CV.

First paper of our lab today nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! EMBL doi.org/10.1038/s41586…

Finally! Principles for ions binding to RNA, derived from a high resolution structure of the bacterial ribosome, very handy for accurate assignment of ions (and by extension, of water molecules) in ribosome/RNA structures 🤓 academic.oup.com/nar/advance-ar…

It's a great pleasure to share our latest collaborative work detailing the composition and structure of the highly rRNA-fragmented mitoribosome from Apicomplexa, such as Plasmodium falciparum and Toxoplasma gondii, now out in Nature Communications rdcu.be/d3R8C

News on ribosome hibernation 🦠Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins: Structure cell.com/structure/full…

academic.oup.com/bbb/advance-ar…

💊Triky přírody: vědci odhalují, jak vznikají nová antibiotika 🧪 Ztráta účinnosti antibiotik v důsledku rostoucí odolnosti patogenních bakterií představuje stále větší výzvu pro moderní medicínu a vědu. Výzkumníkům z Mikrobiologického ústavu AV ČR ve spolupráci s vědci z

Latest work of our lab published in Nature Chemistry

Physiological cost of antibiotic resistance: Insights from a ribosome variant in bacteria 🦠 science.org/doi/10.1126/sc…