Sex-differences catch my attention in Table 1: more balanced in pts w/o O2 (58% M vs. 42% F), but then see more imbalance in O2 (63% M vs 37% F) and invasive MV (73% M vs 27% F) groups - is this due to recruitment? confirmation of higher risk in M, or differential Rx? #rsjc

Also, re: comorbidities and risk of #COVID19, adjusting for them may have been interesting. Groups appear balanced btw dex vs. usual care, and when see breakdown by resp support (Nil vs O2 vs MV), see balance somewhat maintained. ?equal access to Rx despite comorbidities? #rsjc

Re the 8% cross-over of pts in usual care who ended up getting dex eventually, if anything it would have biased results towards null effect (and true effect likely greater) in their ITT analysis - right Matthew Stanbrook? #rsjc

We obviously don't know optimal dex dose (and what factors to adjust based on), but 6mg dex daily for 7 days is a reasonable start based on this. More safety data would have been nice but short course should be ok. #rsjc

Re: baseline demographics, TB and HIV made the list despite such low numbers but missing key confounder data for BMI, which hopefully should be available from hospital records. #rsjc

That's now at least 4 Thursdays in a row, where the line outside the University Health Network #COVID19 assessment centre winds around the front of the hospital, noticeably longer than other days. Are people getting tested so they can make decisions re socializing "safely" on the w/e Abdu Sharkawy?

Stating the obvious here but apparently it needs to be said: You cannot reduce community transmission without having community engagement or representation. This is public health promotion 101.

There is no livelihood if there is no life. An ounce of prevention is worth a pound of cure. Short-term pain for long-term gain. Take your pick - the message is the same. We should aspire and dare to believe in a bold #COVIDzero strategy, since hedging clearly hasn't Doug Ford

Add to list of secondary causes of hypertension: policies and decisions that will inevitably result in more COVID-19 cases, more hospitalizations, increased health system strain, more burnout and mental health issues and most importantly, more lives lost. #lockdownontario

Just telling people to get the #COVID19 #vaccine once it's their turn will not work given high hesitancy. We are actively engaging with communities to openly discuss concerns, answer q's and clarify misconceptions with a diverse set of expert perspectives and relatable voices.

💯 Overcoming this and future pandemics in an increasingly globalized world requires a desire & will to equitably distribute all effective measures – testing kits, PPE, treatments or vaccines – not just to those disproportionately affected within our borders, but beyond as well.

Task forces like ours have been working at the grassroots for months now to address vaccine hesitancy, myths, concerns and questions that are on the minds of these high risk community members. Mosques and Muslim HCWs are ready to deliver culturally competent care if given a shot.

#Ramadan2021 is around the corner! So we've prepared a series of guidelines on how to observe this Ramadan season safely! Follow this thread 🧵:

#RamadanMubarak everyone! Check out this 🧵 on how we can all observe a blessed and #SafeRamadan this year! To see our Ramadan 2021 guidelines, town hall, posters and infographics, please visit cmcovidtf.com #Ramadan2021 #Ramadan2021 [1/14]