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Systemic inflammation impairs myelopoiesis and interferon type I responses in humans nature.com/articles/s4159… Nature Immunology Matthijs Kox Peter Pickkers Henk Stunnenberg

⚠️ Risk-Based Primary Prevention of Heart Failure: A Scientific Statement From the AHA Science‼️ Soc Esp Cardiología SACardiología Asociación Insuficiencia Cardiaca Asociación Cardiología Clínica SEC SEMG 🩺 #OrgullososDeEstarALaCabecera👩‍⚕️👨‍⚕️ SEMERGEN | Médicos de AP #YoPrefieroMFyC Marta Cobo Marcos Rafael de la Espriella Alejandro I. Pérez Cabeza David Vivas Román Freixa Pamias ahajournals.org/doi/10.1161/CI…

Intensive LDL-C lowering with Evolocumab may lead to greater relative reduction in cardiovascular events in patients with autoimmune or inflammatory diseases. André Zimerman @bweber04 ana laura kunzler @rgiuglaino ahajournals.org/doi/full/10.11…

Great talk by EdT at CNIC NIH NHLBI joint meeting on upregulated #HIF in #macrophages: good in ischemic cardiomyopathy, bad in #allograft rejection?

Its happening. The one and only Pilar Alcaide, PhD achievement award. American Society for Investigative Pathology Congratulations

Laissez les bons temps rouler at Scientific Sessions! It’s almost time to submit your science, save your spot, and visit New Orleans for #AHA25, the biggest cardiovascular event of the year. Mark your calendars ⬇️ Jo Chikwe Brahmajee Nallamothu

Excited to share our latest published work showing that marginal metallophilic macrophages from the spleen traffic to the heart and are required for cardiac repair after myocardial infarction. ahajournals.org/doi/pdf/10.116… This raises the possibility of therapeutic splenic

Original Article: Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis (ASPEN phase 3 trial) nej.md/4lBHwUr Editorial: Brensocatib in Bronchiectasis — A New Sheriff in Town? nej.md/4jDIaz7 Science behind the Study: Defanging the Neutrophil to

Interleukin-34-dependent perivascular macrophages promote vascular function in the brain: cell.com/immunity/fullt… Immunity

Hemoglobin-stimulated macrophages drive plaque instability through multiple mechanisms: promoting leaky vessels, thinning protective caps, and preventing calcification. Key insights for cardiovascular diseases! #CVD #macrophage #atherosclerosis ahajrnls.org/44XkoK9

A specialized spleen macrophage population—expressing the markers CD169 and Tim4—mobilizes after MI to drive repair, clear neutrophils & reduce HF risk. A new frontier in cardioprotection via the cardiosplenic axis. @ssbansal_pshvi Sumanth Prabhu, MD ahajournals.org/doi/full/10.11…

Congratulations to NUCATS Institute Career Development Award Scholar alumna Sadiya Khan, MD, MSCI, who has been inducted into ASCI, one of the oldest medical honor societies in the United States — bit.ly/NUCATS-ASCI

Epigenetic modifications in distinct immune and other cell types may act in concert to influence the progression of atherosclerosis. ahajournals.org/doi/full/10.11…

Happy to share a new review: Neural Mechanisms in Cardiovascular Health and Disease | Circulation Research ahajournals.org/doi/full/10.11… Part of a series on Inter-organ communication! Great teamwork Stefanie Dimmeler CVR Tomasz Guzik Cameron McAlpine D Carnevale, S Engelhardt, KA Ziegler

#ICYMI: HFpEF Stem Cells Joseph hill Sanjiv J. Shah, MD Matthew Feinstein Pilar Alcaide, PhD Kris Glinton Gabriele G. Schiattarella Matt DeBerge

Mercedes Carnethon, PhD (Mercedes Carnethon), has taken the baton as the new chair of #PreventiveMedicine and is off and running at full speed! 👏 spr.ly/60144JsGa

TET2 mutant clonal hematopoiesis promotes heart failure with preserved ejection fraction via proinflammatory pathways ambarish, Amanda Tong, Chung Lab, UT Southwestern Medical Center @mattsegar Daniel Daou Wenhuo Hu Naveen Premnath ahajournals.org/doi/full/10.11…

🎧 New #BreakthroughsPodcast Episode! Ed Thorp, PhD, discusses his partnership with Matthew Feinstein, and how EdT's #BasicScience research can respond to the needs of patients. Learn more about his recent discovery by listening to the episode. 🔗 spr.ly/60134rFBW

👏🏼 EdT