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This article provides a summary of CANMAT/ISBD 2018 guidelines with new evidence incorporated for an upto date guidance for clinicians for managing BD. Stay tuned for a more comprehensive update of the guidelines in 2024

An opportunity to work in beautiful British Columbia as an academic faculty member of UBC Psychiatry and new Northern Centre for Clinical Research.

People with bipolar disorder spend 70% of symptomatic periods experiencing depressive symptoms despite current treatments. Thus, more innovative treatments are urgently needed to treat bipolar depression. Our large RCT is recruiting to test if CBD treats depression in BD.

Our pilot trial just published in the Canadian Journal of Psychiatry showed a signal in the post-hoc analysis for the efficacy of CBD in treating depressive symptoms in BD. Hence, starting a large multicentre RCT funded by the CIHR to test efficacy. pubmed.ncbi.nlm.nih.gov/37920963/

High placebo response during the first 2 weeks in both groups impacted primary outcome. Exploratory analysis of data from week 2 onwards shows nearly a 7 point greater reduction in MADRS scores in CBD group vs placebo group. Clearly, need further RCTs to test CBD efficacy.

Congratulations Jill, amazing achievement and very well deserved honor.

Many people who are experiencing bipolar depression don't respond well to currently available treatments. This study will test a new treatment for bipolar depression as our pilot trial showed promising results.

An exciting opportunity to join the newly established concurrent disorders division as an academic faculty member and work with colleagues in the division to build a world class translational research program in concurrent disorders

In a letter published in the NEJM on December 14th, we responded to the comments by colleagues on our paper published in the journal on adjunctive antidepressant maintenance therapy. Our response provides further insights that might help with the interpretation of study results.

Amazing achievement and very well deserved Raymond, congratulations

Just finished giving an opening plenary at Chinese Psychiatric Association annual conference in Changsha, attended by over 5000 people! Amazing to see so many at the congress.

Congratulations Sid, well deserved honor for your amazing contributions.

Honored to be a member of Neurotorium Editorial Board with esteemed colleagues from around the world and support educational initiatives on brain diseases.

Most upto date and pragmatic clinical guidelines for management of MDD. A must read for clinicians.

Congratulations Josh, very well deserved for all your amazing contributions to the field.

All except 1 patient in each group were Bipolar 2 in their study vs less than 50% of patients in our study had bipolar 2, and they used accelerated protocol vs regular protocol in our study. So, very different population and intervention.

Congratulations Birinder, Very well deserved honour for your contributions.

Has there been much progress in treatment of BD and what does the future hold for potential exciting developments? Watch the Neurotorium video that provides a brief summary. neurotorium.org/video/bipolar-…

Join our Symposium on “Novel vistas on the multiple links between mitochondria and mental health” at the ECNP Meeting taking place in Milano this coming Saturday 21.09, at 4:40 PM in Space 3-4 See you soon! With Martin Picard Marsicano Lab Lakshmi Yatham #ECNP2024 #neuroscience

Let's talk about bipolar dsorder! Join me, Dr Hanne Lie Kjærstad and Dr Lakshmi Yatham at the Neurotorium desk at the next ISBD Annual Conference in Reykjavik, Iceland.