Jinchao Hou
@jinchaohou22903
Physician&Researcher in Zhejiang University. Microglia and macrophage in innate immunity #microglia #macrophage #TREM2 #LILRB4
ID: 1776388458594127872
05-04-2024 23:16:44
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Congrats to Jinchao Hou (JinChao Hou) and Yun Chen. Our new study highlights the role of LILRB4 inhibition in enhancing microglial function and reducing amyloid-β accumulation, suggesting LILRB4 as a potential treatment target for AD. science.org/doi/epdf/10.11…
Thrilled to share our work has been highlighted by Dr Monica M. Bertagolli Dr. Monica M. Bertagnolli The Colonna Lab
Excited to share our latest paper: combining anti–PD1 treatment with TREM2 deficiency in mice triggers a proinflammatory response in the gut, promoting the expansion of Ruminococcus gnavus. Congrats to first authors Blanda Di Luccia Martina Molgora Darya Khantakova doi.org/10.1126/sciimm…
Congrats Patrick Rodrigues! Distinct lineages contribute to cDC2 diversity: lymphoid-derived pDC-like and myeloid-derived pre-cDC2 both develop into transcriptionally similar cDC2, crucial for humoral immune responses, and are distinct from pro-DC3 derived DC3. twtr.to/Tr5-h
Our new paper led by Tihana Trsan, collaboration with Xavier Lab, investigating the link between FGFR1OP and Crohn’s disease. Deletion of FGFR1OP, a centrosomal protein, in mouse gut cells disrupts crypt architecture, causing inflammation and fatality cell.com/developmental-…