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Happy to share our newest article Ribbe Hu Labs, published in Science Advances ! If you're interested in why life on Earth didn't die out billions of years ago, dive in! Also, my first paper presenting thread 🧵 science.org/doi/10.1126/sc… #ScienceAdvancesResearch

1/ This graph from Jon Bruner tells an important story: America's current dominance in science only began after the mid-1930s, when persecuted scientists began fleeing universities in Germany and then elsewhere in occupied Europe.

Online Now: YTHDF1 differentiates the contributing roles of mTORC1 in aging dlvr.it/TL2BJm

Your brain, being formed layer by layer [🎞️ 7activestudio]

Pathogen fighters can act as surveillance forces that ferry information from the gut and fat deposits to the brain go.nature.com/4mSLl8H

The geometry of vegetable at its finest [📹 amthuctrunghoa02]

Why does gardening feel so good? 😄🌸🪴 🧠✨ When you dig your hands in the dirt, you may be meeting some friendly bacteria called mycobacterium vaccae (pronounced vahh - kayy). These bacteria can help your brain release more serotonin!

You may ask: “why study ancient enzymes? Who cares what life looked like 3 billion years ago?” Because evolution may hold answers to problems we still struggle with, and it can guide our efforts. New paper from our lab! 🧵

Excited to present our preprint on the structure-function relationship of anaphylatoxin complement receptors. A casual number of 19 structures deciphering ligand recognition mechanisms, G protein/arrestin and species specific signaling. Check it out! biorxiv.org/content/biorxi…

CMplot -A high-quality drawing tool designed for Manhattan plot of genomic analysis github.com/YinLiLin/CMplot

Out Now! Structural insights into light harvesting by antenna-containing rhodopsins in marine Asgard archaea bit.ly/4kl7BGl #LightHarvesting #Rhodopsins #AsgardArchaea

New metabolic reactions uncovered by isotope labeling. Excellent work by Jiang Zhu doi.org/10.1038/s41467…

Residue conservation and solvent accessibility are (almost) all you need for predicting mutational effects in proteins １．A simple model called RSALOR achieves performance on par with or better than most state-of-the-art tools in predicting the effects of mutations on proteins

This chart made by Peter Gleick shows the proposed cuts to science graphically. This is bad for America. Please ask Congress to save science. #FundingScienceSavesLives

Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain: nature.com/articles/s4146…

Antibody-antigen complex prediction results from all-atom benchmark, FoldBench: (1) AlphaFold3 performs best with a success rate of 47.9% while other models have a failure rate exceeding 60%. (2) Increased sampling improves AF3 performance by 2-3% but not for other models.

Nano-scale, mega-impact: nanoPhos delivers 100× phosphoproteomics sensitivity, 70k sites from 1µg, 8k from 10ng! Powered by SPEC, it enables phosphoDVP: deep spatial phosphoproteomics from 1000 neurons, hitting 17k sites, a game changer for spatial omics. biorxiv.org/content/10.110…

Our paper on the use of enhanced sampling to compare different RNA force fields, including HB-CUFIX, is now available. Kudos to Akshaya on the great work. pubs.aip.org/aip/jcp/articl…

medRxiv and bioRxiv cofounder makes Time’s list of 100 people influencing health. time.com/collections/ti…

Alois Fürster Max Planck Society brilliantly lectures on carbene and carbenoid chemistry with Pt, Au or Rh catalysis at the Eschenmoser symposium 2025 D-CHAB