History of micropipettes. Interesting read.

After years of hard work, I am pleased to share our Latest MolCell Paper on how we dissected the function of the only conserved transcription factor NusG in live E.coli. thanks to Achillefs Kapanidis Oliver Pambos Mathew Stracy, Max Gottesman, and all the Kapanidis lab. sciencedirect.com/science/articl…

This immungen elicited a high-quality growth inhibitory response. We also showed that a first dose of this highly focused immunogen, followed by subsequent doses of the broader immunogen, PfRH5, was most effective. Read all about it here: biorxiv.org/cgi/content/sh…

Zebrafish Rock! I'm planning my fish facility and would love to know from the community which company I should get the racks and the whole setup from. Which company did you you go for and what are the pros and especially the cons? Thank you!

Read about a fascinating evolutionary battle between the malaria parasite and the human host in our new pre-print below! Parasites have evolved to bind to inhibitory immune receptor KIR2DL1 while the host has a counter-offensive trick up its sleeve... biorxiv.org/content/10.110…

#MeetTheResearcher Introducing Nawsad Alam from Professor Matt Higgins' lab. As a postdoctoral researcher, Nawsad uses structure-guided approaches to design effective blood-stage #malaria vaccine candidates.

Very excited to share this animation of CaMKII that I created last year for @reichowlab This enzyme regulates the synaptic plasticity underlying learning, memory and cognition 🟡 Kinase domain 🔴 Ca2+ calmodulin-binding domain 🔵 Hub domain #blender #animation #b3d

Delighted to share our data on an improved blood-stage #malaria #vaccine candidate targeting the conserved and essential RH5 invasion complex now published Nature Communications. Congrats to Barney Williams, Lloyd King and the teams University of Oxford and #NIAID. nature.com/articles/s4146…

How does infection with helminths reduce asthma and allergies? Check out our recent paper showing how the helminth secretion product, HpAIR blocks IL-33 signalling. Cunning little parasite! Led by Abhishek Jamwal and fun collaboration with @HenryMcSorley, rdcu.be/dLewH

Excited to share our new vaccine immunogen, designed through structure-guided methods, to prevent Plasmodium vivax. While the PvDBP antigen reduces parasite multiplication when used as a vaccine, it does not protect. PvDBP is also difficult to make. Could we make it better?

Fantastic work from Mehrotra Parul in Kodi Ravichandran lab. I was fortunate enough to watch this project come together from start to finish and Parul's scientific rigour and creativity was a joy to experience. nature.com/articles/s4158…

Delighted to share our latest story with Joshua Tan's group, a deep dive into the natural infection antibody response to RH5, out now in Cell. cell.com/cell/fulltext/… 1/n 🧵

How does the deadly human-infective pathogen Entamoeba histolytica recognise our cells and cause liver abscesses? Check out our latest study, led by @SFGerard2018. Sam shows the structure of the critical amoeba lectin and how it recognises carbohydrates found on human cells.

It's really sad, this closure of veupathdb.org It deprives thousands of parasitologists around the world... At a time when the world is questioning democracy, this illiberal act endangers global research on endemic and neglected diseases. science.org/content/articl…

Postdoc Position Available I am seeking an enthusiastic postdoctoral researcher to join my lab OMRF, studying Astyanax mexicanus cavefish to explore metabolic adaptation. Ideal candidates should have a strong background in metabolism and basic molecular biology skills. Please RT

Second paper from the Pawlowic lab, and first in collaboration with Drug Discovery Unit : science.org/doi/10.1126/sc…

In the silence of chromatin, Toxoplasma whispers change. TgSNF2h sculpts the genome - MORC in the backseat. Some genes wake. Others sleep. A dance of nucleosomes shaping space for life parasite stages to unfold. rdcu.be/ehkWp doi.org/10.1038/s41564…

Thrilled to share this new pre-print, led by Peyton Goddard . If you have ever wanted to know "Where is the gut is the parasite?" this pre-print is for you. 🐮 Thanks to our wonderful collaborators at The Moredun Foundation Frank Katzer David Smith and EMs by Leandro Lemgruber.

Our latest story describes the amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind inhibitory KIR receptors and suppress immune cell function while humans have activating KIR receptors to bind these RIFINs to kill parasites!