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The 2nd BRENDA-LEDUCQ Meeting in Munich started with a lecture by Fabrice Dabertrand, University Colorado: “From impaired cerebral blood flow to cognitive impairment“. The next days were filled with discussion + new ideas for collaborations Foundation Leducq Fabrice Dabertrand

We are happy to present the new BRENDA Leducq Website with all information about the project, talks, meetings, and other news #brenda Foundation Leducq brenda-leducq.de/brenda

Wonderful effort! Congrats Lukas and congrats and thanks to all contributors and collaborators! Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells | Science Signaling science.org/doi/10.1126/sc…

Super happy to share our new work out in Nature Communications, showing that synaptic changes accelerate amyloid-related tau accumulation and spread in #Alzheimer's disease. Many thanks to Michael Schöll and many others! ISD Research, Göteborgs universitet / University of Gothenburg doi.org/10.1038/s41467…

#OriginalResearch: Proteogenomic data integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis #AHAJournals ahajrnls.org/47une7c

A useful resource on the national prevalence of carotid atherosclerosis in China (>10M individuals) JAMA Network Open 👉 increased cIMT (>1mm): 26% | 93% (!) for >80y 👉 plaque: 21% | 87% (!) for >80y 👉 stenosis: 0.6% | 4% for >80y jamanetwork.com/journals/jaman…

Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo academic.oup.com/brain/article-…

First results from 2,500 individuals from eMERGE, a study developed to test genomic risk assessment at a population level. Important PRS data for 10 diseases on: 👉performance 👉feasibility 👉medical actionability 👉translatability nature.com/articles/s4159…

And the awards go to Larissa Breuer DZNE Research Center, Judit González Gallego ISD Research, & Clemens Sauter Hertie-Institut für klinische Hirnforschung (HIH). Congratulations! Thank you to all who participated. Your contributions & active participation made this meeting so special! #StemCellTuebingen TübingenNeuroCampus

Age-related decline in brain endothelial cell (BEC) function contributes critically to neurological disease.(…) A study by isd investigators 👉Todorov-Völgyi Katalin Judit González Gallego et al. just published on Nature Aging read more here isd-research.de/isd-research

Very excited to share that our DELiVR method is now open access published @NatureMethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. nature.com/articles/s4159… by Doris Kaltenecker Rami @[email protected]

What honor to host the ISGC workshop, here at the preciousLMU St.-Vinzenz-Haus Munich City Great Keynote Lectures and Scientific Sessions and social activities #strokegenetics strokegenetics.org

The 30th ISGC Workshop is in full swing! Thank you to everyone contributing to talks, posters and vivid discussions 🧠🩸🧬🔬 And a big thank you to our host Rainer Malik and the ISD Research 🎉✨️🎊

ISD teams gathered for annual scientific retreat to present their projects and discuss work. There were presentations from Ph.D. students, a poster session, invited speaker talks, and an amazing three minute thesis competition. Dominik Paquet Sarah Jaekel

October 15-17 9th ICAA in Munich, ISD co-organizing 9th Interational Conference on Cerebral Amyloid Angiopathy in Munich. Experts will present latest developments in CAA research ranging from basic research to studies in humans. Sign up now: icaaconference.org/registration-d…

Excited to share our newest work showing that neuroinflammation parallels tau spread in 4R tauopathies, suggesting a key role of microglia in tau progression. Many thanks to Maura Malpetti, Sebastian Roemer, Johannes Levin, Günter Höglinger and MatthiasBrendel doi.org/10.1002/mds.29…

Authors from ISD Research, ZMB and colaborators develop repair approaches to reverse the effects of pathogenic mutations in protease HTRA1. nature.com/articles/s4146…

Finally out today! Very proud of this story: Innate immune memory after Stroke drives remote organ pathology This study was led by superstar-postdoc Alba Simats and X-less Sijia Zhang. Cell cell.com/cell/fulltext/…

Did you ever wonder why the risk for subsequent vascular events is increased after a first stroke or MI? Our answer, out now in nature nature.com/articles/s4158… A story about NETosis, DNA-sensing and inflammasome activation. Spearheaded by Stefan Roth and Jiayu Cao.

ERC Starting Grant 2024 for Anna-Sophia Wahl and her team for studying fundamental principles of neuronal repair after stroke. isd-research.de/isd-research-n…