Ever wonder what the #3Dgenome folding🔺of a Neanderthal looked like?! Could it hold any clues as to where and why we have DNA 🧬and trait differences? Check out our Capra Lab, Pollard lab & Geoff Fudenberg lab collaboration bioRxiv biorxiv.org/content/10.110… 1/8

This morning I have been pondering the polygenicity of cancer traits in the context of germline versus somatic mutations: youtube.com/watch?v=K8u4ke…

"Methylation risk scores (MRS) were constructed for 607 phenotypes. [...] When added to a baseline set of predictive features, MRS significantly improved the imputation of 139 outcomes, whereas the PRS improved only 22" medrxiv.org/content/10.110…

"Integrated data assets such as the Biobank at the CCPM are key resources for population health monitoring in response to public health emergencies, such as the COVID-19 pandemic." medrxiv.org/content/10.110…

2morrow is Twosday: 2-22-22

"Most plant species depend on animals to disperse their seeds. [...] Analyses indicate that past defaunation has severely reduced long-distance seed dispersal, cutting by more than half the number of seeds dispersed far enough to track climate change." science.org/doi/10.1126/sc…

A Redditor ran every street in their neighborhood and made this gorgeous #dataviz from the tracking data. Source: reddit.com/r/dataisbeauti…

When listeners pay close attention to stories, their heart rates synchronize "On one level, the findings are uplifting simply because they demonstrate how stories unite us" pnas.org/post/journal-c…

In the 1970s & 80s, anthropologists working in small-scale, non-industrial societies fastidiously noted down what people were doing throughout the day. I’ve been exploring the data & am struck by one of the most popular activities: doing nothing. [thread]

Ancient neural pathways that evolved in a world of scarcity now drown in a world of abundance. A “fire hose” of dopamine? npr.org/2022/03/31/109…

A deadly plant allows miner bees to evade kleptoparasitism: "An extreme case of exclusive codependence of pollinator and plant, one of just a few cases in which a flower species relies on just a single insect for pollination" colorado.edu/asmagazine/202…

An atlas of genetic scores to predict multi-omic traits biorxiv.org/cgi/content/sh… #bioRxiv

boxplot straws: an eco-friendly way to drink a soda? 🫧#savetheturtles🐢 #dataviz

It’s a Monday! Yay!

Counter the weaponization of genetics research by extremists nature.com/articles/d4158… "Ultimately, we as scientists need to ensure that our analyses are conducted and presented to underscore — not undermine — the biological reality of our shared humanity."

What rules should govern genomic data collection, access, and use?open.substack.com/pub/datavalues…