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Great work elucidating off-target flortaucipir signals and how they co-occur with various histological correlates. Make sure you check it out!

If you’ve ever had trouble sleeping at night or maybe dozed off in a session this week, come and sit in on this session!

It’s a REALLY cool project, highly recommend taking a moment to check it out!

#サマソニ OSAKAこの後YOASOBI！19:55からMountain Stageです🗻 会場は広大なスタジアム。皆さんの大きな声が聴きたい！よろしくお願いします💥💥💥💥

Our latest review Gowoon Son, PhD (she/her) delves into how tauopathies, including Alzheimer's, affect the suprachiasmatic nucleus (SCN), the brain clock in humans and how tauopathy impacts this crucial area for circadian regulation. Neuromodulatory Subcortical Systems PIA Sleep Research Society Sleep and Circadian Rhythms Grinberg Lab

first time since 2020 that I cannot find a seat at the Caltrain. Great to see the ridership of public mass increasing again. Much better for the environent

Exciting session and discussion! It’s been a pleasure to share thoughts & science 🧠👩‍🔬with my beloved collagues Lea T. Grinberg, M.D, Ph.D Sharon Naismith Claire Sexton T. Neylan! Thank you to #CONy2024 and Alzheimer's Association organizers

Bringing some updates to my project! Come check out what our lab is up to, we’re working on a broad range of projects ranging from tau post translational modifications to selective vulnerability of populations to the pathophysiology of sleep disturbances in AD, and more!

Watch this very informative talk from Dr. Grinberg on which neurons that are responsible to control our sleep, what to know about our own sleep patterns and what sleep disturbance means on dementia patients. grinberglab.ucsf.edu/news/professor…

it is already being fantastic! thanks to the Alzheimer's Association , Claire Sexton @IgorCamargoFfor allowing us to get together investigators from the bay area in person and connect us with the word. Kudos to my co-organisers Shea J Andrews Alexander Ehrenberg Kristine Yaffe ISTAART

Prof. Russell Swerdlow, the plenary speaker @aaicneuro SF @ucsf hub in the intriguing mitochondrial cascate hypothesis for @alzheimer. i just learned that peripheral mitochondrial also get dysfunctional in AD. Shea J Andrews ISTAART Alzheimer's Association UC San Franciscomac

Celebrating one of our very accomplished SRA students, Yumi Yang, before she embarks on her new academic journey at Yale. Go for it Yumi! Lea T. Grinberg, M.D, Ph.D

Celebrating our amazing lab members and their achievements is even better on a sunny day! ☀️👏 Grinberg Lab UCSF Ian M. Oh (오규식) Gowoon Son, PhD (she/her) Abhijit Satpati Yuheng (Jonathan) Chen UCSF MAC

Abhijit Satpati will present #aaic24 novel data showing how a pattern of distinctive vulnerability of #sleep-promoting LHA neurons in #alzheimer variants tracks well with clinical sleep profile Grinberg Lab UCSF Neuromodulatory Subcortical Systems PIA

Excited to share our latest on #Tauopathies! 🧠 Using iPSC der-neurons with MAPT V337M mutations and novel antibodies, we showed caspase-6 cleaved tau plays a neurotoxic role. Caspase inhibitors prevented this toxicity, New therapeutic avenues? tinyurl.com/yrp9b4rx UCSF MAC

These studies are real team science. Grateful to The Rainwater Charitable Foundation where Michelle Arkin and I met, seeding funds from UC San Francisco & Alzheimer's Association for D13 and D402 antibodies, and The National Institute on Aging (NIA) funds for cell development with Celeste Karch, Sally Temple, and David Butler. Grinberg Lab UCSF

The real star here is Panos Theofilas, who led these studies. If you're attending #AAIC24, check out Liara Rizzi, PhD, MSc's poster on Monday (#828) to see the results from our homebrew Quanterix assay, developed to detect D13-tau in CSF. 🌟🔬 #Neuroscience #Research #Alzheimers

Neus Falgàs has lead an effort to put together a unique longitudinal cohort, possible because of Hospital Clínic Raquel Sánchez-Valle which undertake LC & hypothalamus imaging and get neurotransmitters measured. on the way to map Neuromodulatory Subcortical Systems PIA in #alzheimer in vivo. Watch her #AAIC24

Poster #120 The human brain clock in neuromodulatory subcortical nuclei Neuromodulatory Subcortical Systems PIA is vulnerable to tau pathology in the absence of amyloid, examined by Digital Spatial Profiler NanoString Grinberg Lab UCSF Lea T. Grinberg, M.D, Ph.D UCSF MAC see more on grinberg lab #AAIC24 below. Sleep and Circadian Rhythms

Grateful to the Unitat d’Alzheimer i altres Trastorns Cognitius team and especially to these great panel of women research scientist for leading our latest article #womeninSTEM 👩‍🔬🧠🥼Andrea del Val Agnès Pérez-Millan Bea Bosch Raquel Sánchez-Valle Lea T. Grinberg, M.D, Ph.D Hospital Clínic UCSF MAC Global Brain Health Institute AWAREPIA