It is a common misperception that WHI excluded symptomatic menopausal women; it only excluded symptomatic women who could not stop HT.

One in two postmenopausal women in the United States will suffer from a fracture related to osteoporosis during their lifetime.

In general, the alpha receptors are involved in the reproductive system while the beta receptors are active in other body tissues.

The decreasing amount of ovarian estrogen that characterizes the perimenopause, affects as many as 300 different body parts.

Hot flushes may begin in the perimenopausal period months or years before menopause.

WHI was the first randomized trial to directly assess whether oral CEE plus MPA affected CHD risk in healthy postmenopausal women.

The WHI intervention lasted a median of 5.6 years in CEE plus MPA and 7.2 years in CEE alone, with 13 years of cumulative follow-up

1 in 4 women are affected by osteoporosis after menopause

The balance of benefits and risks for HT is most favorable within the first ten years of menopause, or up to around 60 years of age

The “timing” hypothesis suggests older women treated with HT for the first time have no benefit and may have early harm

While the vasomotor symptoms of menopause generally improve over time, vaginal symptoms usually worsen and do not improve without treatment

14th Annual Women’s Health Update at the Mayo Clinic starts today

The approach used to manage the signs and symptoms of menopause often boils down to which of the body’s estrogen receptors to affect

The most common menopause symptoms are vasomotor symptoms, usually described as night sweats, hot flashes, flushes, and vaginal dryness

Menopause is the absence of menstruation for a full year from the last menstrual period, a definition that has been consistent for decades

WHI is the largest clinical trial investigating common causes of morbidity and mortality among postmenopausal women

The “timing” hypothesis suggests younger symptomatic women treated with HT at menopause onset may be protected from CHD

The mean age of the women participating in the hormone therapy arm of the WHI trial was 63 years

The WHI included randomized trials of a low-fat dietary pattern, calcium and vitamin D supplementation, and postmenopausal hormone use

Before menopause, women are 3X less likely to have a heart attack than men. After menopause, they have an equal chance