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The latest human GENCODE releases for Human (45) and Mouse (M34), have just been released. They're available via gencodegenes.org and visible in Ensembl genome browser as part of Ensembl 111 ensembl.org

👀👇☀️Dear Colleagues, there are 2 weeks left to submit an abstract at our October conference #ncRNA2024! Why come? -Brilliant international speakers -fantastic city -loads of networking + social time -high probability of selected talks. So come join us!

You might know someone but you will definitely come across people whom you do not know that are somehow connected to you It’s a pleasure to discover these connecting 🧵s #BoG24 Known: #PEC2 data harmonization Me ↔️ Julio Collado Vides ↔️ Guigó Lab Unknown: #recount3 ➡️ GencodeGenes

That might be a gin&tonic in my hand, but it still holds true that #recount3 is a wonderful resource and super useful in our annotation efforts! Great to meet you 🇲🇽 Leonardo Collado-Torres!!

🥳👇🧠Calling all RN-Aficionados! The deadline for #ncRNA2024 has been extended to 11 June. Remaining places are filling fast so be sure to submit your Abstract ASAP. The RNA Society Jr RNA Scientists NCCR RNA & Disease GencodeGenes NCCR RNA & Disease The RNA Society #RNA #ncRNA #lncRNA

We had an amazing attendance this morning for the Ensembl workshop at #ESHG2024 #berlin 🎉 EMBL-EBI Training EMBL-EBI

If you are attending #ESHG2024 come and talk to us at 20.063.D in the poster area about our initiative to annotate non-canonical ORFs Ensembl #bioinformatics #genomics #berlin

DNA and RNA sequencing methods are rapidly evolving, each with its own benefits and challenges. Find out how the Long-read RNA-Seq Genome Annotation Assessment Project (LRGASP) can help you choose the right long-read sequencing method for your research. nature.com/articles/s4159…

Out today: the Long-read RNA-Seq Genome Annotation Assessment Project (LRGASP) paper, featuring contributions from many GENCODE members, a systematic evaluation of methods for long-read transcript detection and quantification: nature.com/articles/s4159…

I´m thrilled to see our #LRGASP paper published in Nature Methods today. This is the work of many to benchmark long-read methods for transcriptomics, and a must-read paper for those using lrRNA-seq. Special thnks to Francisco Pardo-Palacios and Brooks Lab (1/6) rdcu.be/dJ9ev

We are excited to publish our second-ever Registered Report! The #LRGASP Consortium evaluated various methods for transcript identification and quantification using long-read sequencing technologies. AnaConesa The Sheynkman Lab Brooks Lab Ali Mortazavi nature.com/articles/s4159…

1/ GENCODE continue to work on the annotation of non-canonical translations identified by Ribo-seq, and are pleased to support this preprint which examines which ORFs express protein products: biorxiv.org/content/10.110…

2/ Relatively few Ribo-seq ORFs have peptide support from tryptic digests, although substantial numbers are supported by immunopeptidomics data. Many thanks to our large number of collaborators Eric Deutsch Rob Moritz @johnprensner @s_heesch

3/ How do we interpret immunopeptidomics support in biological terms? How many of these ORFs are bona fide proteins as opposed to unstable peptides or aberrant products? What does this mean for annotation? These are open questions and our work continues... HGNC UniProt

We're pleased to share our GENCODE 2025 NAR database paper: tinyurl.com/3etnfw4j Thanks to all our collaborators, friends and users. This is now the main citation for our resource, and hopefully also a good explanation of how and why we do what we do.