Vous voulez voir un truc scandaleux? Alors lisez-bien le fil qui va suivre car c’est votre pognon qui a financé tout ça. ☠️ Je vais vous parler du gaspillage dans la santé 🏴‍☠️ Accrochez-vous ça pique 🧶👇 (THREAD) (1/9)

Great review on mitochondrial lipids Katsu Funai why is it critical for the outer and inner membranes to have different lipid composition? cell.com/cell-metabolis…

Just trying to look all handsome🥰

Agreed - understanding how impaired mitochondrial energy transformation capacity increases inflammation and other phenotypes is key Many cytokines labeled as "inflammation" arise from excessive energy resistance (éR) osf.io/preprints/osf/…

I see a granola bar!!!

The nucleus is more like a passive a hard drive. Not much dynamic computation there it seems. Mitochondria appear to contribute both the heart (energizing) and brain (processing) functions for the cell A mitocentric perspective

BillOckham Martin Picard What if inflammation and disease is a repair process? Atherosclerosis shores things up to prevent a more catastrophic event. High fevers burn off pathogenic bacteria. Tumors are excess garbage control. Just asking, are we 100% sure what we're labelling as dysfunction actually is?

Inflammation is a signal that something needs to change, that something physiologically and/or energetically unsustainable is happening

Sean Powell Martin Picard Sure,Hoehn, 2009 positioned IR as a protective mechanism & I agree w/ him. HIF-1a is beneficial when (e)HIF-1a but deleterious when (i)HIF-1a. My criteria ab those processes is REVERSIBILITY to homeostasis-the moment Inflammation fails to do that & becomes persistent 1 is toast🤷

Sean Powell BillOckham Martin Picard Inflammation aims to 1) clear the cause of perturbation, 2) adaptation to noxious stimuli and 3) retention of homeostasis (which is accompanied by tissue repair). It's not dysfunctional but coming at the expense of changes in function of organs (HF, IR...).

Vidéo-mystère du jour. A votre avis, que voyons-nous ici ? N'hésitez pas à poster votre proposition en commentaire, je donnerai la réponse en fin de journée.

Sean Powell BillOckham Martin Picard drmalcolmkendrick.org/2017/06/06/wha…

How can you deny giving me a boop? You can't. It just can't be done. I'll take one million boops, please!❤️

カピバラ渋滞中。 #カピバラ #水豚 #capybara #伊豆シャボテン動物公園

New repository of science papers on: 1- Mitochondrial Diversity 2- Mitochondrial Diseases 3- Mind-Mitochondria Connection 4- Energetics of Aging 5- Mitochondrial Biomarkers 6- Energetics of Health picardlab.org/publications Thank you Cynthia Liu for organizing!

I am looking at an antibody to purchase, I am wondering who is the mouse Brian. :D Save the mouse Brian?

⚠️Spoiler alert! L'autisme: -n'est pas contagieux -est mieux reconnu et identifié (d'où l'"épidémie"🙄) -n'est toujours pas du aux vaccins (et non) -les causes, multifactorielles, sont déjà connues: génétiques, environnementaux (💊 comme Depakine), prématurité... #IgnoranceCrasse

Jeremy and Luke 😊

A paper published in Nature Nanotechnology, in 2024, using only male mice with this methodology for the behavioral tests! Are you serious Nature?

Thank you Alexandre Dumoulin @axonsalex.bsky.social , this movie is mind blowing! We are immensely proud that, thanks to you, our SPY555-FastAct actin probe is represented at the Nikon Small World in Motion competition! We'll keep our fingers crossed for the competition 🤞