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IBD Genetics Digestive Disease Week #DDW2025 session. First up from our lab - Dalin Li presenting on UC vs CD and other phenotypes. More than 100 loci distinguish these phenotypes. PRS are different across phenotypes. Some novel mechanisms implicated. IBD at Cedars-Sinai.

Next up IBD genetics session Digestive Disease Week #DDW2025 Ashley Beecham presenting novel findings through local ancestry approaches in our Hispanic studies. NOD2, HLA implicated & novel finding implicating RIPK2 pathway in complicated CD on African ancestry. IBD at Cedars-Sinai Maria T. Abreu

👀 our Poster of Distinction on #IUS in ASUC (Sa1816)! #DDW2025 IBD at Cedars-Sinai InternationalBowelUS iUSCAN Digestive Disease Week

3rd presentation from IBD at Cedars-Sinai in the Digestive Disease Week #DDW2025 IBD genetics section Minsuk Kim presenting on a multiplex African American family with IBD and SpA implicating a frameshift variant in IFNAR1 in driving disease in this family.

Prof Yoichi Kakuta - Tohoku University & former lab member IBD at Cedars-Sinai group presenting on NUDT15 variants effects on pregnancy in IBD. Provocative findings suggesting utility of pre-conception testing for NUDT15. Great to see him doing this important work.

Busy 1st day #DDW2025 for our group: 3 🧬 oral presentations followed by computational pathology & radiomic posters suggesting clinical utility in ASUC, post-op CD recurrence, EIMs & others. Lots more to come with AI/ML in histopathology and radiomics. IBD at Cedars-Sinai Phillip Gu

Day 2 DDW. Another busy day. V. nice of #DDW2025 organizers 2 put our lab IBD at Cedars-Sinai AI posters back 2 back 2 back. Radiomic features assoc with UC2CD dx switch, multi-modal model for predicting PSC, & visceral/subcutaneous fat assoc. with disease extent and behaviour in IBD

Afimkibart (TL1-A inhibitor) demonstrated efficacy for objective EP in moderate-severe UC #colitis in phase 2b clinical trial w no dose response, presented by Dr Vipul Jairath MBChB DPhil. The competition in this MOA class is intensifying #DDW2025 #IBD

Anti-TL1-a 3.0! Duvakitug demonstrated efficacy primarily for endoscopic endpoints in mod-severe #crohnsdisease in a first of its kind in #IBD basket trial (parallel UC, CD). Well tolerated Vipul Jairath MBChB DPhil #DDW2025 #IBD

Our offerings Day 3 at #DDW2025 - Philip Debbas demonstrating association between IBD phenotypes and blood group antigens. And Dylan Shiramizu’s work on his computational pathology approach to identify small bowel features associated with clinical phenotypes.

📩 Take home from our talks Christopher Gardner Digestive Disease Week is the importance of ⬆️ fibre intake & ⬆️ variety of dietary fibres consumed as they all have differing benefits for host & microbiome. Dietitian support is 🔑 for those struggling with symptoms/concerns on high fibre diets 🥦

Visit Angelo Autiak Ayii Chol (POHER scholar alum) poster 1045 Digestive Disease Week® (DDW) #DDW2025

Great day at Anfield meeting Mo Salah Mohamed Salah and lifting the Premier League trophy with family. Well nearly! Liverpool FC 20 times Champions of England. #YNWA ‘Campione, Campione’

Very excited to share a comprehensive (150+ page) new resource for caregivers/ families of children living with IBD and/or autoimmune liver disease. This Caregiver Coping resource addresses a broad array of common concerns and questions, from navigating diagnosis, to managing

Ha ha! Happy Birthday! Ngorongoro is one of the most spectacular things I’ve seen!

𝐔𝐍𝐙𝐀 𝐂𝐮𝐥𝐭𝐮𝐫𝐞 𝐃𝐚𝐲 𝟐𝟎𝟐𝟓 A vibrant celebration of Zambia’s cultural heritage at the University of Zambia! From traditional music and dance to food and art, the event showcased unity, identity & sustainable development through culture. #UNZACultureDay2025 #UNZA

Congratulations Jonathan Segal #TOTMUN ! Enjoy! Better season than Arsenal! I think Angie has played a blinder conning everyone all season and then releasing the Mourinho version of Spurs in the final!! Man U ha ha ha! Happy days!

Campiones! #BackOnOurPerch #YNWA

HANG IT IN THE LOUVRE 🏆🏆🏆🏆🏆