Have you checked out our latest Nature Communications article? Learn about how #phosphorylation can impact the conformation of the ubiquitous protein #HSP90 thus opening therapeutic avenues & drugging the undruggable #epichaperome #CancerResearch #PrecisionMedicine nature.com/articles/s4146…

How do stressors remodel #brain function before symptoms emerge? &network-centric intervention strategies as a promising avenue for disease-modifying #therapy in AD #Alzheimers #epichaperomes #neuroscience #SystemsBiology #networkbiology #drugdiscovery researchsquare.com/article/rs-593…

🚨 Our review "#Epichaperomes: Redefining #ChaperoneBiology and Therapeutic Strategies in Complex Diseases" is now out in @RSC_ChemBiol as an Accepted Manuscript! #DrugDiscovery #NetworkMedicine #SystemsBiology #PrecisionTherapeutics doi.org/10.1039/D5CB00…

Epichaperomes: Redefining Chaperone Biology and Therapeutic Strategies in Complex Diseases - now published in RSC Chemical Biology pubs.rsc.org/en/content/art…

frontiersin.org/journals/molec…

Accepted manuscript alert! Our review "#Epichaperomes: Redefining #ChaperoneBiology and Therapeutic Strategies in Complex Diseases" is now out in @RSC_ChemBiol #DrugDiscovery #NetworkMedicine #SystemsBiology #PrecisionTherapeutics pubs.rsc.org/en/content/art…

Sahil presented earlier this month at #AAIC2025 in Toronto Alzheimer's Association. This work was supported by BrightFocus Foundation & The National Institute on Aging (NIA) and aims to advance #precisionmedicine in #neurodegeneration through the development of small molecule probes for #epichaperome imaging in #Alzheimers.

Are you attending #ACSFall2025? Keep an eye out for Chander S Digwal, he will be presenting Targeting Aberrantly Glycosylated GRP94: Conformational Dynamics and Implications for Drug Design early next week! #GRP94 #epichaperomics #glycosylation #proteinproteininteraction #PPI

Don't miss him in the MEDI: General Poster Session Tuesday, August 19, 2025, 6:00 PM – 8:00 PM Hall C – Walter E. Washington Convention Center Poster Board #: 577! #ACSFall2025 #posterpresentation #GRP94 #epichaperomics #glycosylation #drugdevelopment #medicinalchemistry

🌞🥼Summer intern shoutout! Ishaan presented his work from the last few months under the mentorship of Dr. Sahil Sharma sahil sharma at the student symposium last week . Congratulations Ishaan!🥳 We cannot wait to see what your future holds 🤓

Online now - PTMs as molecular encoders: reprogramming chaperones into epichaperomes for network control in disease dlvr.it/TMkyft

In memory of Len Neckers, whose pioneering work on #HSP90 and #PTMs laid the foundation for how we think about chaperone regulation. Our latest Trends in Biochemical Sciences review builds on this legacy to explore the formation and function of #epichaperomes. doi.org/10.1016/j.tibs…

⭐️Very excited to share that our article 'PTMs as Molecular Encoders: Reprogramming Chaperones into Epichaperomes for Network Control in Disease' is out online now in Trends in Biochemical Sciences #PTMs #HSP90 #epichaperome #PPI #neuroscience sciencedirect.com/science/articl…

Fantastic review by Gabriela Chiosis and team connecting the epichaorome with the chaperone code

Now accepting applications for our 2026 #Cancer Biology & Cancer Engineering programs. Aspiring scientists & engineers will solve fundamental problems in biology & conduct research & develop technology that will help understand, diagnose, & treat cancer. bit.ly/3WUiuo1

🍂Happy Autumn! It was a busy summer in @ChiosisLabMSKCC! We had 10 high school & undergraduate students join us for mentorship. We are so grateful for the opportunity to part of their research journeys & looking forward to hearing about all of their future achievements!😃🥼

🚨Publication alert! The final version of our article is OUT NOW in Trends in Biochemical Sciences. @ChiosisLabmskcc is honored to have been selected as the cover feature for this issue - cover art by a VI4 Artist in Residence. Check out the review article here: doi.org/10.1016/j.tibs…

Chiosis Lab Trends in Biochemical Sciences Dive deeper into the concept behind our Trends in Biochemical Sciences TIBS cover article! Read more on Springer Nature Communities communities.springernature.com/posts/when-mod… #Epichaperome #PTMs #NetworkBiology #SystemsBiology #TrendsBiochem #NatureCommunities

How can post-translational modifications rewrite cellular networks? Read communities.springernature.com/posts/how-post… Springer Nature Trends in Biochemical Sciences #Epichaperome #PTMs #NetworkBiology #SystemsBiology #MolecularChaperones #CellBiology #Neurodegeneration #CancerResearch

Proteins rarely work alone. Their functions emerge from networks of interactions—dynamic connections that continuously reorganize to maintain cellular balance. What happens when this balance is lost? This blog dives into our Trends in Biochemical Sciences review article: communities.springernature.com/posts/how-post…