K.G. Jebsen Center for Cardiac Biomarkers (@crg_norway) 's Twitter Profile
K.G. Jebsen Center for Cardiac Biomarkers

@crg_norway

Akershus University Hospital, Norway. Led by Prof. Torbjørn Omland. Areas of focus: Cardiovascular biomarkers, cardio oncology, heart failure, risk prediction

ID: 1065518744942841856

linkhttps://www.med.uio.no/klinmed/forskning/grupper/hjerte-thorax/index.html calendar_today22-11-2018 08:13:59

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Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

#NTproBNP is a fantastic biomarker for prediction of #HF events, but can it be used to predict incident #VentricularArrhythmias? In this study led by Nur Sourour 💫 of patients treated with #ICD, we made some interesting findings K.G. Jebsen Center for Cardiac Biomarkers 🧵1/5 onlinelibrary.wiley.com/doi/10.1002/cl…

Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

🚺 have higher LVEF than 🚹! In this elegant study using ventriculography, Wu et al show that women with ‘normal LVEF’ have worse prognosis than ‘high LVEF’ heart.bmj.com/content/early/… In the editorial Carolyn Lam and I argue for sex-specific LVEF cutoffs heart.bmj.com/content/early/…

Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

RCT data consistently show that Omega-3 suppl increase AF risk ahajournals.org/doi/full/10.11… In this substudy of the #OMEMI trial we add novel data from thumb-ECG screening and serum EPA/DHA, supporting a causal relation between omega-3 (EPA) and AF! sciencedirect.com/science/articl… 🧵 1/4

RCT data consistently show that Omega-3 suppl increase AF risk ahajournals.org/doi/full/10.11…

In this substudy of the #OMEMI trial we add novel data from thumb-ECG screening and serum EPA/DHA, supporting a causal relation between omega-3 (EPA) and AF!

sciencedirect.com/science/articl…

🧵 1/4
Hjerteforum (@hjerteforum) 's Twitter Profile Photo

Akutt høyre ventrikkelsvikt❗️ Lær mer om denne alvorlige og komplekse tilstanden i en glimrende oversiktsartikkel skrevet av Erik Qvigstad. legeforeningen.no/contentassets/…

Akutt høyre ventrikkelsvikt❗️
Lær mer om denne alvorlige og komplekse tilstanden i en glimrende oversiktsartikkel skrevet av Erik Qvigstad.

legeforeningen.no/contentassets/…
Hjerteforum (@hjerteforum) 's Twitter Profile Photo

*Kardiorenalt syndrom* Hva betyr det når kreatinin stiger? Hva skal vi gjøre? Nefrolog Bård Waldum gir oss en flott oversikt i denne artikkelen: legeforeningen.no/contentassets/…

*Kardiorenalt syndrom* 
Hva betyr det når kreatinin stiger? Hva skal vi gjøre?
Nefrolog Bård Waldum gir oss en flott oversikt i denne artikkelen:

legeforeningen.no/contentassets/…
Hjerteforum (@hjerteforum) 's Twitter Profile Photo

Perkutan behandling av alvorlig trikuspidalinsuffisiens (kant-mot-kant) er et nytt og spennende behandlingsprinsipp som er i bruk også i Norge. I denne oversiktsartikkelen dekker Kristoffer Russel fra Oslounivsykehus evidens, pasientseleksjon mm. legeforeningen.no/contentassets/…

Perkutan behandling av alvorlig trikuspidalinsuffisiens (kant-mot-kant) er et nytt og spennende behandlingsprinsipp som er i bruk også i Norge.

I denne oversiktsartikkelen dekker Kristoffer Russel fra <a href="/Oslounivsykehus/">Oslounivsykehus</a> evidens, pasientseleksjon mm.

legeforeningen.no/contentassets/…
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

Stiftelsen Kristian Gerhard Jebsen Annual Symposium about «Internationalization in Research» was amazing with talks from Nobel laureate Edvard Ingjald Moser and my own mentor scottdavidsolomon who travelled from Harvard Medical School to share his experience of hosting 107 (!!) international scholars 🙏🏻

<a href="/stiftkgj/">Stiftelsen Kristian Gerhard Jebsen</a>  Annual Symposium about «Internationalization in Research» was amazing with talks from Nobel laureate <a href="/EdvardMoser/">Edvard Ingjald Moser</a> and my own mentor <a href="/scottdsolomon/">scottdavidsolomon</a> who travelled from <a href="/harvardmed/">Harvard Medical School</a> to share his experience of hosting 107 (!!) international scholars 🙏🏻
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

In 13,900 HF-free individuals, we identified 37 proteins consistently associated with incident HF independent of traditional risk factors. The majority with higher risk, but also a few with lower risk! NT-proBNP was (by far) the strongest, followed by SVEP1, WFDC2 and ANGPT2

In 13,900 HF-free individuals, we identified 37 proteins consistently associated with incident HF independent of traditional risk factors. The majority with higher risk, but also a few with lower risk!

NT-proBNP was (by far) the strongest, followed by SVEP1, WFDC2 and ANGPT2
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

We now have RCT evidence for #ARNI in all 4 corners of the LVEF-by-acuity spectra in HF ◻️ #PARADIGM #PARAGON #PIONEER #PARAGLIDE We summarize the data showing striking consistency in effects up to normal EF, irresp of acuity! Carolyn Lam JACC Journals sciencedirect.com/science/authSh…

We now have RCT evidence for #ARNI in all 4 corners of the LVEF-by-acuity spectra in HF ◻️

#PARADIGM 
#PARAGON
#PIONEER
#PARAGLIDE

We summarize the data showing striking consistency in effects up to normal EF, irresp of acuity! <a href="/lamcardio/">Carolyn Lam</a> <a href="/JACCJournals/">JACC Journals</a> 

sciencedirect.com/science/authSh…
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

Can #troponin be used to rule out cardiac abnormalities after #COVID19 ? In this study led by PhD-student Tarjei Øvrebotten 💫, we measured hs-TnT during hospitalization, after 3 and 12 months and associated that with changes in #echo and #CMR link.springer.com/article/10.118…

Can #troponin be used to rule out cardiac abnormalities after #COVID19 ?

In this study led by PhD-student <a href="/Tarjeivrebotten/">Tarjei Øvrebotten</a> 💫, we measured hs-TnT during hospitalization, after 3 and 12 months and associated that with changes in #echo and #CMR

link.springer.com/article/10.118…
K.G. Jebsen Center for Cardiac Biomarkers (@crg_norway) 's Twitter Profile Photo

We are thrilled to announce that our group leader and mentor Torbjørn Omland Torbjørn Omland has been appointed member of The Norwegian Academy of Science Det Norske Videnskaps-Akademi ⭐️ 📷 DNVA/Thomas B. Eckhoff

We are thrilled to announce that our group leader and mentor Torbjørn Omland <a href="/OmlandRn/">Torbjørn Omland</a> has been appointed member of The Norwegian Academy of Science <a href="/DNVA1/">Det Norske Videnskaps-Akademi</a> ⭐️

📷 DNVA/Thomas B. Eckhoff
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

🔥off the press in EJHF European Society of Cardiology Journals EJHF Editor-in-Chief Changes in #6MWT in HFrEF during uptitration of #GDMT is a predictor of survival independent of changes in NT-proBNP and NYHA - supporting it as a surrogate outcome in HF trials. 🚶‍♂️50m increase = 17%⬇️☠️ onlinelibrary.wiley.com/doi/10.1002/ej…

🔥off the press in EJHF <a href="/ESC_Journals/">European Society of Cardiology Journals</a> <a href="/EJHFEiC/">EJHF Editor-in-Chief</a> 

Changes in #6MWT in HFrEF during uptitration of #GDMT is a predictor of survival independent of changes in NT-proBNP and NYHA - supporting it as a surrogate outcome in HF trials.

🚶‍♂️50m increase = 17%⬇️☠️

onlinelibrary.wiley.com/doi/10.1002/ej…
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

More data on #NTproBNP 🤓 In 🚺 who had gestational diabetes we found a strong link between ⬇️ NTproBNP and ⬆️ insulin resistance, which may explain part of the “BNP-obesity paradox’ and differences by race. link.springer.com/article/10.118… K.G. Jebsen Center for Cardiac Biomarkers @UniOslo_ME

More data on  #NTproBNP 🤓

In 🚺 who had gestational diabetes we found a strong link between ⬇️ NTproBNP and ⬆️ insulin resistance, which may explain part of the “BNP-obesity paradox’ and differences by race.

link.springer.com/article/10.118…

<a href="/CRG_Norway/">K.G. Jebsen Center for Cardiac Biomarkers</a> @UniOslo_ME
Peder L. Myhre 🫀 (@pmyhre) 's Twitter Profile Photo

Elevated #NatriureticPeptides and #troponins are strong predictors of #HF events, but ever wondered if these biomarkers predict worsening cardiac structure & function? We analyzed NT-proBNP, TnT and TnI in a/w serial echo in ~2000 👤 in #ARIC Just published in Circulation 🧵 /5

Elevated #NatriureticPeptides and #troponins are strong predictors of #HF events, but ever wondered if these biomarkers predict worsening cardiac structure &amp; function?

We analyzed NT-proBNP, TnT and TnI in a/w serial echo in ~2000 👤 in #ARIC

Just published in <a href="/CircAHA/">Circulation</a> 
🧵 /5