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Molecular mechanism of complement inhibition by the trypanosome receptor ISG65 biorxiv.org/content/10.110…

Our latest preprint reveals an amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind to inhibitory KIR receptors and suppress immune cell function while humans evolved activating KIR receptors to bind these RIFINs to kill parasites!

Read about a fascinating evolutionary battle between the malaria parasite and the human host in our new pre-print below! Parasites have evolved to bind to inhibitory immune receptor KIR2DL1 while the host has a counter-offensive trick up its sleeve... biorxiv.org/content/10.110…

Always important to network into the wee hours... #EMBLMalaria @EMBL

Very proud of Nawsad Alam, giving his talk about how we are trying to make the best possible blood stage malaria vaccine at BioMalPar 2024

All that 'networking' has me tired! Great week of talks/posters and loved meeting more of this fantastic community! #EMBLmalaria

🎮 Researchers demonstrated that activating killer immunoglobulin-like receptors can recruit NK cells to target a pathogen and reveal a potential role for activating immune receptors in controlling #malaria infection. nature | go.nature.com/3G2MQjM