The addition of CPC to hemispheric surgery may prevent post-hemispherectomy hydrocephalus. journals.lww.com/neurosurgery/A…

‼️ PUBLISHED Nature Genetics 📰 Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development 🧑‍🤝‍🧑 Joseph G. Gleeson Xiaoxu Yang 정창욱 and team 🔽 go.nature.com/3GvGSUU

♥️Roses are red, violets are blue. Nature Genetics February issue is live.. Just for you😍 👇🏿 go.nature.com/3Yx9aGc

Is mesial temporal lobe epilepsy (MTLE) attributable to genetic factors? It turns out, yes! Our work on somatic genetics of MTLE is out in JAMA Neurology today, arguing that somatic variants in the hippocampus may account for a subset of MTLE cases. A🧵… jamanetwork.com/journals/jaman…

Key point: Achieving seizure freedom in cases with HME may correlate with improved post-operative developmental outcomes doi.org/10.1111/epi.17… #Hemimegalencephaly #Hemispherectomy #epilepsysurgery #epilepsy #ILAE #UCLA International League Against Epilepsy Epilepsia Wiley Neuro

The illustration for this publication was also featured on the cover of the issue. Congratulations! #skullbase #stanfordneurosurgery

Dr. Westley Phillips and team uncover key genetic markers in focal pediatric epilepsy, linking brain-specific somatic variants to seizure origins. 🧠🔍 neurology.org/doi/10.1212/NX… #brain #EpilepsyAwareness #Neurosurgery #Neurology #neuroscience #Genetics #Biology

Chromosomal 22q11.2 deletions increase risk for meningomyelocele, one of the most severe and common forms of spina bifida, a new Science study finds. 📄: scim.ag/6PS

The P2RIME Lab is currently recruiting post-doctoral fellows with PhD level training in Molecular Biology and the Neurosciences. Apply through link: postdocs.stanford.edu/prospective/op…

Are you a medical student or neurosurgery resident interested in Functional Neurosurgery, but seeking more research or clinical mentorship than what's at your own institution? Learn more about the new #ASSFN AMPLify Mentorship Program. ASSFN assfn.org/healthcare-pro…

Continuing #EpilepsyAwarenessMonth we focus on a study from Dr. Westley Phillips and the PRIME.lab that looks at the correlation between the electrophysiologic and genetic signatures of epilepsy. It was found that regions with higher mutation burden were more epileptogenic.

November is Epilepsy Awareness Month. Dr. H. Westley Phillips, pediatric neurosurgeon at Stanford Children's, specializes in epilepsy surgery and leads research on epilepsy genetics. Inspired by children’s resiliency, he views neurosurgery as a team sport with kids as star players.

#EpilepsyAwarenessMonth: Corpus callosotomy is an important treatment for atonic seizures in drug resistant epilepsy. Corpus Callosotomy Ablation (CCA) via MR-guided stereotactic laser interstitial thermal therapy (LITT) is an emerging minimally invasive treatment option.

Signaling pathway through KRAS leading to the development of pediatric cerebral AVMs. New, free article in Journal of Neurosurgery, check it out: doi.org/10.3171/2024.6…

#TBT Dr. E. Latunde Odeku, the 1st African-American neurosurgeon trained in the U.S., broke barriers at Howard & Michigan before returning to Nigeria in 1961. There, he revolutionized neurosurgical care & mentored future leaders. A true global pioneer. 🌍 🧠 #ASBNHistory #ASBNorg

Very proud of these ladies for representing the PRIME Lab at the 2024 American Epilepsy Society Meeting in LA! Danielle (UCD Senior, AES BRIDGE intern) presented her summer work. Julie Uchitel & Sarah Rockwood (Stanford Med) presented some of our clinical projects. Way to go 🎉

D’Gama et al. report that minimally invasive genetic testing using sEEG electrodes detects brain-specific mosaic variants in focal epilepsy, offering promise for precision diagnostics and treatment. Please read at: buff.ly/J8KgnX4

Dr. H. Westley Phillips co-led groundbreaking research on analyzing DNA from stereo-EEG electrodes, revealing mosaic epilepsy variants. This innovative technique helps diagnose drug-resistant epilepsy using previously discarded tissue samples. Learn more: academic.oup.com/braincomms/art…