5yo boy with bowel intussusception due to ____
A) lymphoma
B) bowel reduplication
C) meckels diverticulum
#GIPath #PediPath #PathTwitter #pathology
🙏🖼️WebPathology

Follicular lymphoma with BCL2 rearrangement by FISH & unusual overexpression of CCND1 by IHC (CD5 & SOX11 negative; CCND1 rearrangement negative by FISH). This rare finding has been reported previously➡️shorturl.at/lzDOU but is worth to be aware of #hemepath #lymsm #PathX

Definitely a sign of spring...rosettes of TFH cells on 2 new cases of Nodular LP Hodgkin/B-cell lymphoma in just 1 day. 🌺 #hemepath

Primary large B-cell lymphoma of the CNS: Cyclin-D1 highlights endothelial cells in brain tissue, however its pattern of expression could be misinterpreted as positivity in neoplastic cells. Comparison to MUM1 & PAX5 is helpful to avoid this pitfall #hemepath #lymsm #PathX

Follicular lymphoma with abundant extracellular eosinophilic material, mimicking amyloid deposition: An unsual variant to be aware of #hemepath #lymsm #pathtwitter #MedEd #SoMe

Check a similar but more prominent case by Sanam Loghavi, MD صنم لغوی 🔬🧬 Blood Journal➡️ ashpublications.org/blood/article/…

Large B-cell lymphoma involving the testicle with a germinal center-like phenotype (CD10+BCL6+MUM1-): May occur in < 10% of primary large B-cell lymphoma of the testis, however, it should raise the suspicion of disseminated systemic DLBCL #hemepath #lymsm #surgpath #Pathx #MedX

Swing by our fellowship booth and discover the awesome opportunities Penn has for pathology residents/medical students. We've got a bunch of top-notch fellowships waiting for you to explore! Penn Path & Lab Medicine USCAP #uscap2024 #fellowshipfair

Middle-aged patient with bowel thickening. What’s your differential diagnosis? #hemepath #gipath

76 yo man, neck LN. whats all that pink stuff? 🕵🏻‍♂️

AML with MECOM (EVI1) translocation. Commonly associated with pronounced megakaryocytic dysplasia and hyperplasia. Some patients can present with thrombocytosis. The prognosis is poor.

Pathologists! Check out this case of Dermatopathic lymphadenopathy (DL). Lots of Langerhans cells (LC), but it’s not LC histiocytosis, because the LC are in paracortex (not sinuses), they have a dendritic configuration, are MUM1+, and melanin is present. See PMID 35877199.

Today is the day…. Our book is here 🤩
It’s beautiful.. and has that fabulous new book smell 😍
Get yours today and let us know what you think ☺️
Tremendous thanks to Genevieve Crane, MD, PhD Timothy Craig Allen, MD, JD, FCAP and all the authors 🙏🏻

link.springer.com/book/10.1007/9…

I can't just see a photogenic Warthin tumor and NOT post it. I'm only human.

#entpath #pathtwitter #pathx

Happy #humpdayHemepath y'all!

Kid with anemia - what's the finding in this bone marrow?

Michigan Pathology Michigan Medicine University of Michigan Medical School @UMich 𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM ASH Hem-Onc Fellows Network 🏮

#hemepath megakaryoblasts. Bleb bleb bleb

#hemepath comparison of B-ALL cells to normal small lymphocytes in bone marrow

Kaposi sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8)-associated multicentric Castleman disease (KSHV/HHV8-MCD) is a lymphoproliferative disorder with:

🩸 idiopathic multicentric Castleman disease-like morphology (Figure 1 below)
🩸 KSHV/HHV8-infected plasmablasts (Figure 2

🩸Indolent T lymphoblastic proliferation (IT-LBP) is an extra-thymic non-clonal expansion of T-lymphoblasts

🩸It occurrs alone or in association with other disorders, including Castleman disease (as illustrated in below Figures 1-3) and others (myasthenia gravis, hepatocellular

Adrenal mass arising from a(n) ___ process
A) neoplastic
B) ectopic
#hemepath #bstpath #gupath #pathresidents #pathtwitter

Childhood myelodysplastic neoplasm-low blasts, hypocellular➡️
🩸Arises in children and adolescents (<18 years of age)
🩸Cytopenia involving one or more lineages
🩸Dysplastic changes in one or more lineages, involving at least 10% of cells
🩸<5% bone marrow blasts and <2%