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A new JAMA study published during #AAIC24 found a blood test had high diagnostic accuracy for identifying Alzheimer disease among adults with cognitive symptoms. This test could lead to early diagnosis and may facilitate timely access to new treatments. ja.ma/46nbWCM

🚨Publication in JAMA 🚨 Blood biomarkers to detect Alzheimer’s disease in primary and secondary care, published today in JAMA led by Sebastian Palmqvist: jamanetwork.com/journals/jama/…

In adults without cognitive impairment and with low brain Aβ levels, a blood test combining p-tau217 and Aβ42/40 better predicted longitudinal changes in brain Aβ load than individual biomarkers. ja.ma/4fe0rBL BioFINDER #AAIC24

Hope you had a very good first day and enjoyed the welcome reception. We continue #AAIC24 with more science from our group!

Atrophy of what brain regions are selectively associated with α-synuclein pathology during preclinical stages? In this JAMA Neurology paper we found that the nucleus basalts of Meynert was in particular affected, which was related to impairment in executive function.

I'm happy to share our paper on harmonizing tau PET in Alzheimer's disease that was just published in Alzheimer's & Dementia 🧠 📈 🚀 doi.org/10.1002/alz.13… 🧵[1/7]

Most viewed in the last 7 days from JAMA: Study prospectively evaluates a clinically available Alzheimer disease blood test in primary care and secondary care using predefined biomarker cutoff values. ja.ma/3yv1SLm

The 10 biggest medical research papers from this week (in my opinion!) 1. A blood test for Alzheimer disease, which improved diagnostic accuracy - by dementia specialists - from 73% to 91% jamanetwork.com/journals/jama/… 🧵

I am so proud of being part of this great team!!! 😊

Can we identify people who are at increased risk of developing amyloid-β pathology in the coming years? This study indicates that plasma p-tau217 together with Ab42/40 can do the job, which is important for identifying suitable people for primary prevention studies.

Trending in #Medicine: ooir.org/index.php?fiel… 1) Blood Biomarkers to Detect Alzheimer Disease (JAMA) 2) Paleoradiological investigations of the screaming woman mummy (Frontiers - Medicine) 3) Epigenetic impact of vegan vs. omnivorous diets on aging (BMC Medicine) 4)

At AAIC 2024, phospho-tau assays look ready for primary and secondary care. Lund University @wustl Banner Alzheimer's ow.ly/QPzg50SV3Tp

Well done Gemma!!!

Very excited to see our paper on neuroimaging to predict dementia in MCI as the Editor's Pick on the JAMA Neurology website. You can find our open access paper here: jamanetwork.com/journals/jaman… Special thanks to Oskar Hansson RikOssenkoppele and JAMA Neurology

Experts stipulate performance standards for amyloid blood tests. @AAIC2024 @wustl Lund University ow.ly/RqYY50T4uw7

🚨 Available as a preprint – The Alzheimer's Association #pTau round robin study 🚨 📣 33 different ways to measure #blood #pTau 📣 Mass Spec, semi & fully-auto immunoassays 📣 #pTau217 consistently best 📣 Corr. between assays = optimism for standardisation medrxiv.org/content/10.110…

You did a fantastic job Alexa with this study! I am truly impressed! 🤩

Big thanks to the BioFINDER team for two great days! During our workshop we sharpened our visions for the future, optimized our database structure and learnt from the clinicians how different clinical assessments are done.

Today Linda Karlsson did her halftime seminar as a PhD student in the BioFINDER team. She really excelled! A really fantastic performance by Linda, but also by the great examinators, profs Daniel Ferreira (KI) and Rodrigo Moreno (KTH). I learnt a lot today. 😊